Greater extent of blood‐tumor TCR repertoire overlap is associated with favorable clinical responses to PD‐1 blockade

With the widespread use of programmed death receptor‐1 (PD‐1) blockade therapy, sensitive and specific predictive biomarkers that guide patient selection are urgently needed. T‐cell receptor (TCR) repertoire, which reflects antitumor T‐cell responses based on antigen specificity, is expected as a no...

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Detalles Bibliográficos
Autores principales: Aoki, Hiroyasu, Ueha, Satoshi, Nakamura, Yoshiaki, Shichino, Shigeyuki, Nakajima, Hiromichi, Shimomura, Manami, Sato, Akihiro, Nakatsura, Tetsuya, Yoshino, Takayuki, Matsushima, Kouji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353913/
https://www.ncbi.nlm.nih.gov/pubmed/34014607
http://dx.doi.org/10.1111/cas.14975

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