APOE4-mediated Alzheimer disease and “Vascular”—“Meningeal Lymphatic” components: towards a novel therapeutic era?

A three-dimensional graphic design representation of the potential role of meningeal vessels in Alzheimer disease. Although there are major differences between APOE4(+) and APOE4(−) Alzheimer disease cases (described in detail in the Comment article by Mentis and colleagues), the figure depicts the...

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Detalles Bibliográficos
Autores principales: Chen, Zhangying, Schwulst, Steven J., Mentis, Alexios-Fotios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354095/
https://www.ncbi.nlm.nih.gov/pubmed/34376823
http://dx.doi.org/10.1038/s41380-021-01242-7
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author Chen, Zhangying
Schwulst, Steven J.
Mentis, Alexios-Fotios A.
author_facet Chen, Zhangying
Schwulst, Steven J.
Mentis, Alexios-Fotios A.
author_sort Chen, Zhangying
collection PubMed
description A three-dimensional graphic design representation of the potential role of meningeal vessels in Alzheimer disease. Although there are major differences between APOE4(+) and APOE4(−) Alzheimer disease cases (described in detail in the Comment article by Mentis and colleagues), the figure depicts the clearance of macromolecules and other solutes from meningeal lymphatic vessels. Cover image: Ella Maru Studio.
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spelling pubmed-83540952021-08-11 APOE4-mediated Alzheimer disease and “Vascular”—“Meningeal Lymphatic” components: towards a novel therapeutic era? Chen, Zhangying Schwulst, Steven J. Mentis, Alexios-Fotios A. Mol Psychiatry Comment A three-dimensional graphic design representation of the potential role of meningeal vessels in Alzheimer disease. Although there are major differences between APOE4(+) and APOE4(−) Alzheimer disease cases (described in detail in the Comment article by Mentis and colleagues), the figure depicts the clearance of macromolecules and other solutes from meningeal lymphatic vessels. Cover image: Ella Maru Studio. Nature Publishing Group UK 2021-08-10 2021 /pmc/articles/PMC8354095/ /pubmed/34376823 http://dx.doi.org/10.1038/s41380-021-01242-7 Text en © The Author(s), under exclusive licence to Springer Nature Limited 2021, corrected publication 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comment
Chen, Zhangying
Schwulst, Steven J.
Mentis, Alexios-Fotios A.
APOE4-mediated Alzheimer disease and “Vascular”—“Meningeal Lymphatic” components: towards a novel therapeutic era?
title APOE4-mediated Alzheimer disease and “Vascular”—“Meningeal Lymphatic” components: towards a novel therapeutic era?
title_full APOE4-mediated Alzheimer disease and “Vascular”—“Meningeal Lymphatic” components: towards a novel therapeutic era?
title_fullStr APOE4-mediated Alzheimer disease and “Vascular”—“Meningeal Lymphatic” components: towards a novel therapeutic era?
title_full_unstemmed APOE4-mediated Alzheimer disease and “Vascular”—“Meningeal Lymphatic” components: towards a novel therapeutic era?
title_short APOE4-mediated Alzheimer disease and “Vascular”—“Meningeal Lymphatic” components: towards a novel therapeutic era?
title_sort apoe4-mediated alzheimer disease and “vascular”—“meningeal lymphatic” components: towards a novel therapeutic era?
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354095/
https://www.ncbi.nlm.nih.gov/pubmed/34376823
http://dx.doi.org/10.1038/s41380-021-01242-7
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AT mentisalexiosfotiosa apoe4mediatedalzheimerdiseaseandvascularmeningeallymphaticcomponentstowardsanoveltherapeuticera

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