Cargando…

It takes more than tau to tangle: using proteomics to determine how phosphorylated tau mediates toxicity in neurodegenerative diseases

Detalles Bibliográficos
Autores principales:	Pires, Geoffrey, Drummond, Eleanor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2021
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354106/ https://www.ncbi.nlm.nih.gov/pubmed/33818497 http://dx.doi.org/10.4103/1673-5374.310680

Ejemplares similares

Neurofibrillary tangles in Alzheimer's disease: elucidation of the molecular mechanism by immunohistochemistry and tau protein phospho-proteomics
por: Metaxas, Athanasios, et al.
Publicado: (2016)

Tau mRNA Metabolism in Neurodegenerative Diseases: A Tangle Journey
por: da Costa, Paulo J., et al.
Publicado: (2022)

Tau phosphorylation by GSK-3β promotes tangle-like filament morphology
por: Rankin, Carolyn A, et al.
Publicado: (2007)

The Importance of Tau Phosphorylation for Neurodegenerative Diseases
por: Noble, Wendy, et al.
Publicado: (2013)

Tau interactome and RNA binding proteins in neurodegenerative diseases
por: Kavanagh, Tomas, et al.
Publicado: (2022)

Tangled tau: Active pathology or footprint of disease?
por: Higham, James P.
Publicado: (2017)

Tangles, Toxicity, and Tau Secretion in AD – New Approaches to a Vexing Problem
por: Gendreau, Kerry L., et al.
Publicado: (2013)

Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat
por: d’Orange, Marie, et al.
Publicado: (2018)

A Tangled Web – Tau and Sporadic Parkinson's Disease
por: Wray, Selina, et al.
Publicado: (2010)

Tau accumulation in the nucleus accumbens in tangle-predominant dementia
por: Kawakami, Ito, et al.
Publicado: (2014)

Aluminum and Tau in Neurofibrillary Tangles in Familial Alzheimer’s Disease
por: Mold, Matthew John, et al.
Publicado: (2021)

CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease
por: Horie, Kanta, et al.
Publicado: (2023)

Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer’s disease and not in other tauopathies
por: Pires, Geoffrey, et al.
Publicado: (2019)

Tau Phosphorylation, Aggregation, and Cell Toxicity
por: Avila, J., et al.
Publicado: (2006)

RNA editing of microtubule-associated protein tau circular RNAs promotes their translation and tau tangle formation
por: Welden, Justin Ralph, et al.
Publicado: (2022)

Fluent molecular mixing of Tau isoforms in Alzheimer’s disease neurofibrillary tangles
por: Dregni, Aurelio J., et al.
Publicado: (2022)

Plasma amyloid-beta oligomer and phosphorylated tau: diagnostic tools for progressive Alzheimer’s disease
por: An, Seong Soo A., et al.
Publicado: (2023)

Targeting Prion-like Cis Phosphorylated Tau Pathology in Neurodegenerative Diseases
por: Albayram, Onder, et al.
Publicado: (2018)

Human TAU(P301L) overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain
por: Cosacak, Mehmet I., et al.
Publicado: (2017)

A simple human cell model for TAU trafficking and tauopathy-related TAU pathology
por: Bell, Michael, et al.
Publicado: (2021)

Re-examining tau-immunoreactive pathology in the population: granulovacuolar degeneration and neurofibrillary tangles
por: Hunter, Sally, et al.
Publicado: (2015)

Tiny Toes to Tau Tangles: Down's Syndrome and Its Association With Alzheimer's Disease
por: Puttagunta, Sri Madhurima, et al.
Publicado: (2022)

Brain delivery of quercetin-loaded exosomes improved cognitive function in AD mice by inhibiting phosphorylated tau-mediated neurofibrillary tangles
por: Qi, Yao, et al.
Publicado: (2020)

Tau imaging in neurodegenerative diseases
por: Dani, M., et al.
Publicado: (2015)

Highly Selective Tau-SPECT Imaging Probes for Detection of Neurofibrillary Tangles in Alzheimer’s Disease
por: Ono, Masahiro, et al.
Publicado: (2016)

Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads
por: Salvadó, Gemma, et al.
Publicado: (2023)

The Harvard method of Tau calculation is incorrect
por: Horning, Andrew, et al.
Publicado: (2019)

Granulovacuolar Degenerations Appear in Relation to Hippocampal Phosphorylated Tau Accumulation in Various Neurodegenerative Disorders
por: Yamazaki, Yuu, et al.
Publicado: (2011)

Root patterning: it takes two to tangle
por: Scheres, Ben, et al.
Publicado: (2016)

Small molecules to target tau amyloid aggregation
por: Manglano-Artuñedo, Zoe, et al.
Publicado: (2023)

Caspase-Cleaved Tau Co-Localizes with Early Tangle Markers in the Human Vascular Dementia Brain
por: Day, Ryan J., et al.
Publicado: (2015)

Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer’s disease
por: Cicognola, Claudia, et al.
Publicado: (2018)

Assessment of Tau Tangles and Amyloid-β Plaques Among Super Agers Using PET Imaging
por: Hoenig, Merle C., et al.
Publicado: (2020)

APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles
por: Ferrari-Souza, João Pedro, et al.
Publicado: (2023)

In-Cell NMR Study of Tau and MARK2 Phosphorylated Tau
por: Zhang, Shengnan, et al.
Publicado: (2018)

The use of localized proteomics to identify the drivers of Alzheimer's disease pathogenesis
por: Drummond, Eleanor, et al.
Publicado: (2017)

Taking More Than a Fair Share? The Migration of Health Professionals from Poor to Rich Countries
por: Dovlo, Delanyo
Publicado: (2005)

Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity
por: Ando, Kanae, et al.
Publicado: (2016)

Extracellular vesicles drive tau spreading in Alzheimer's disease
por: Ruan, Zhi
Publicado: (2021)

The Evolution of Tau Phosphorylation and Interactions
por: Trushina, Nataliya I., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_q9pvhlucp7ioc00he68f8sg1ii