Cargando…
Cy3-RgIA-5727 Labels and Inhibits α9-Containing nAChRs of Cochlear Hair Cells
Efferent cholinergic neurons inhibit sensory hair cells of the vertebrate inner ear through the combined action of calcium-permeable α9α10-containing nicotinic acetylcholine receptors (nAChRs) and associated calcium-dependent potassium channels. The venom of cone snails is a rich repository of bioac...
Autores principales: | Fisher, Fernando, Zhang, Yuanyuan, Vincent, Philippe F. Y., Gajewiak, Joanna, Gordon, Thomas J., Glowatzki, Elisabeth, Fuchs, Paul Albert, McIntosh, J. Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354143/ https://www.ncbi.nlm.nih.gov/pubmed/34385908 http://dx.doi.org/10.3389/fncel.2021.697560 |
Ejemplares similares
-
RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia
por: Christensen, Sean B., et al.
Publicado: (2017) -
From Crystal Structures of RgIA4 in Complex with Ac-AChBP to Molecular Determinants of Its High Potency of α9α10 nAChR
por: Pan, Si, et al.
Publicado: (2021) -
RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic Pain in Rats
por: Huynh, Peter N., et al.
Publicado: (2019) -
Limited Efficacy of α-Conopeptides, Vc1.1 and RgIA, To Inhibit Sensory Neuron Ca(V) Current1,2,3
por: Wright, Andrew B., et al.
Publicado: (2015) -
RgIA4 Prevention of Acute Oxaliplatin-Induced Cold Allodynia Requires α9-Containing Nicotinic Acetylcholine Receptors and CD3(+) T-Cells
por: Huynh, Peter N., et al.
Publicado: (2022)