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Prostatic artery embolization for giant prostatic hyperplasia: a single-center experience
OBJECTIVE: To describe the safety and efficacy of prostatic artery embolization (PAE) in patients with a markedly enlarged prostate. MATERIALS AND METHODS: This was a retrospective study including 18 consecutive patients (mean age, 74 years) with benign prostatic hyperplasia, all with a prostate vol...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354184/ https://www.ncbi.nlm.nih.gov/pubmed/34393287 http://dx.doi.org/10.1590/0100-3984.2020.0096 |
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author | de Assis, André Moreira Moreira, Airton Mota Carnevale, Francisco Cesar Lanz-Luces, José Ramón |
author_facet | de Assis, André Moreira Moreira, Airton Mota Carnevale, Francisco Cesar Lanz-Luces, José Ramón |
author_sort | de Assis, André Moreira |
collection | PubMed |
description | OBJECTIVE: To describe the safety and efficacy of prostatic artery embolization (PAE) in patients with a markedly enlarged prostate. MATERIALS AND METHODS: This was a retrospective study including 18 consecutive patients (mean age, 74 years) with benign prostatic hyperplasia, all with a prostate volume ≥ 200 cm(3), who were enrolled to receive PAE for the treatment of moderate-to-severe lower urinary tract symptoms. RESULTS: The PAE procedure was technically successful in 17 patients (94.4%). During follow-up, clinical failure (defined as an International Prostate Symptom Score [IPSS] ≥ 8) was observed in two (11.1%) of those 18 patients. At 3 months of follow-up, there was significant improvement over baseline in all relevant outcome measures: total IPSS (from 15.7 to 2.9); IPSS quality of life score (from 5.2 to 1.0); prostate specific antigen (from 11.4 to 1.82 ng/mL); peak urinary flow rate (from 7.45 to 18.6 mL/s); prostate volume (from 252.4 to 151.6 cm(3)); and post-void residual volume (from 143.7 to 28.3 mL)-p < 0.05 for all. Of the 18 patients, one (5.6%) presented detachment of prostate tissue and self-limited hematuria, which did not require specific treatment. CONCLUSION: In patients with a markedly enlarged prostate, PAE proved to be safe and effective, resulting in significant improvements in clinical, imaging, and urodynamic parameters. |
format | Online Article Text |
id | pubmed-8354184 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
record_format | MEDLINE/PubMed |
spelling | pubmed-83541842021-08-13 Prostatic artery embolization for giant prostatic hyperplasia: a single-center experience de Assis, André Moreira Moreira, Airton Mota Carnevale, Francisco Cesar Lanz-Luces, José Ramón Radiol Bras Original Article OBJECTIVE: To describe the safety and efficacy of prostatic artery embolization (PAE) in patients with a markedly enlarged prostate. MATERIALS AND METHODS: This was a retrospective study including 18 consecutive patients (mean age, 74 years) with benign prostatic hyperplasia, all with a prostate volume ≥ 200 cm(3), who were enrolled to receive PAE for the treatment of moderate-to-severe lower urinary tract symptoms. RESULTS: The PAE procedure was technically successful in 17 patients (94.4%). During follow-up, clinical failure (defined as an International Prostate Symptom Score [IPSS] ≥ 8) was observed in two (11.1%) of those 18 patients. At 3 months of follow-up, there was significant improvement over baseline in all relevant outcome measures: total IPSS (from 15.7 to 2.9); IPSS quality of life score (from 5.2 to 1.0); prostate specific antigen (from 11.4 to 1.82 ng/mL); peak urinary flow rate (from 7.45 to 18.6 mL/s); prostate volume (from 252.4 to 151.6 cm(3)); and post-void residual volume (from 143.7 to 28.3 mL)-p < 0.05 for all. Of the 18 patients, one (5.6%) presented detachment of prostate tissue and self-limited hematuria, which did not require specific treatment. CONCLUSION: In patients with a markedly enlarged prostate, PAE proved to be safe and effective, resulting in significant improvements in clinical, imaging, and urodynamic parameters. Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem 2021 /pmc/articles/PMC8354184/ /pubmed/34393287 http://dx.doi.org/10.1590/0100-3984.2020.0096 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article de Assis, André Moreira Moreira, Airton Mota Carnevale, Francisco Cesar Lanz-Luces, José Ramón Prostatic artery embolization for giant prostatic hyperplasia: a single-center experience |
title | Prostatic artery embolization for giant prostatic hyperplasia: a single-center experience |
title_full | Prostatic artery embolization for giant prostatic hyperplasia: a single-center experience |
title_fullStr | Prostatic artery embolization for giant prostatic hyperplasia: a single-center experience |
title_full_unstemmed | Prostatic artery embolization for giant prostatic hyperplasia: a single-center experience |
title_short | Prostatic artery embolization for giant prostatic hyperplasia: a single-center experience |
title_sort | prostatic artery embolization for giant prostatic hyperplasia: a single-center experience |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354184/ https://www.ncbi.nlm.nih.gov/pubmed/34393287 http://dx.doi.org/10.1590/0100-3984.2020.0096 |
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