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N-(4-Hydroxyphenyl) Retinamide Suppresses SARS-CoV-2 Spike Protein-Mediated Cell-Cell Fusion by a Dihydroceramide Δ4-Desaturase 1-Independent Mechanism

The membrane fusion between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and host cells is essential for the initial step of infection; therefore, the host cell membrane components, including sphingolipids, influence the viral infection. We assessed several inhibitors of the enzy...

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Detalles Bibliográficos
Autores principales:	Hayashi, Yasuhiro, Tsuchiya, Kiyoto, Yamamoto, Mizuki, Nemoto-Sasaki, Yoko, Tanigawa, Kazunari, Hama, Kotaro, Ueda, Yusuke, Tanikawa, Takashi, Gohda, Jin, Maeda, Kenji, Inoue, Jun-ichiro, Yamashita, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354230/ https://www.ncbi.nlm.nih.gov/pubmed/34106748 http://dx.doi.org/10.1128/JVI.00807-21

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