Antibodies from Rabbits Immunized with HIV-1 Clade B SOSIP Trimers Can Neutralize Multiple Clade B Viruses by Destabilizing the Envelope Glycoprotein

The high viral diversity of HIV-1 is a formidable hurdle for the development of an HIV-1 vaccine. Elicitation of broadly neutralizing antibodies (bNAbs) would offer a solution, but so far immunization strategies have failed to efficiently elicit bNAbs. To overcome these obstacles, it is important to...

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Detalles Bibliográficos
Autores principales: van Haaren, M. M., McCoy, L. E., Torres, J. L., Lee, W., Cottrell, C. A., Copps, J. L., van der Woude, P., Yasmeen, A., de Taeye, S. W., Torrents de la Peña, A., Moore, J. P., Burton, D. R., Klasse, P. J., Ward, A. B., Sanders, R. W., van Gils, M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354326/
https://www.ncbi.nlm.nih.gov/pubmed/34076487
http://dx.doi.org/10.1128/JVI.00094-21

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