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Induced endothelial cells from peripheral arterial disease patients and neonatal fibroblasts have comparable angiogenic properties

Induced endothelial cells (iECs) generated from neonatal fibroblasts via transdifferentiation have been shown to have pro-angiogenic properties and are a potential therapy for peripheral arterial disease (PAD). It is unknown if iECs can be generated from fibroblasts collected from PAD patients and w...

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Detalles Bibliográficos
Autores principales: Hywood, Jack D., Sadeghipour, Sara, Clayton, Zoe E., Yuan, Jun, Stubbs, Colleen, Wong, Jack W. T., Cooke, John P., Patel, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354451/
https://www.ncbi.nlm.nih.gov/pubmed/34375370
http://dx.doi.org/10.1371/journal.pone.0255075