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Evaluation of the mediastinal-thoracic volume ratio on postmortem computed tomography

OBJECTIVES: The aim of this study was to measure the mediastinal-thoracic volume ratio (CTR_VOL) on PMCT as a more accurate version of traditional CTR, in order to assess the terminal positional relationship between the heart and lungs in the different causes of death with regard to age, gender, BMI...

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Autores principales: Chatzaraki, Vasiliki, Ebert, Lars C., Thali, Michael J., Haidich, Anna-Bettina, Ampanozi, Garyfalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354949/
https://www.ncbi.nlm.nih.gov/pubmed/33909145
http://dx.doi.org/10.1007/s00414-021-02593-0
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author Chatzaraki, Vasiliki
Ebert, Lars C.
Thali, Michael J.
Haidich, Anna-Bettina
Ampanozi, Garyfalia
author_facet Chatzaraki, Vasiliki
Ebert, Lars C.
Thali, Michael J.
Haidich, Anna-Bettina
Ampanozi, Garyfalia
author_sort Chatzaraki, Vasiliki
collection PubMed
description OBJECTIVES: The aim of this study was to measure the mediastinal-thoracic volume ratio (CTR_VOL) on PMCT as a more accurate version of traditional CTR, in order to assess the terminal positional relationship between the heart and lungs in the different causes of death with regard to age, gender, BMI, cardiomegaly, and lung expansion. MATERIALS: Two hundred fifty consecutive postmortem cases with pre-autopsy PMCT and full forensic autopsy were retrospectively evaluated. The lungs and the mediastinum were manually segmented on the PMCT data and the correspondent volumes were estimated in situ. CTR_VOL was calculated as the ratio of the mediastinal to the thoracic volume. The volume measurements were repeated by the same rater for the evaluation of the intrarater reliability. Age, gender, body weight and height, heart weight at autopsy, and cause of death were retrieved from the autopsy reports. Presence of lung expansion was radiologically evaluated in situ. RESULTS: CTR_VOL was positively associated with age and BMI but not with gender and was higher for cardiomegaly compared to normal hearts, lower for asphyxiation-related deaths compared to cardiac deaths and intoxications, and lower for cases with lung expansion. The intrarater reliability was excellent for the calculated volumes of both lungs and mediastinum. CONCLUSION: The results of the present study support CTR_VOL as a tool to assess the relationship between the heart and lungs in situ, which differs significantly between the studied cause of death categories. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00414-021-02593-0.
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spelling pubmed-83549492021-08-25 Evaluation of the mediastinal-thoracic volume ratio on postmortem computed tomography Chatzaraki, Vasiliki Ebert, Lars C. Thali, Michael J. Haidich, Anna-Bettina Ampanozi, Garyfalia Int J Legal Med Original Article OBJECTIVES: The aim of this study was to measure the mediastinal-thoracic volume ratio (CTR_VOL) on PMCT as a more accurate version of traditional CTR, in order to assess the terminal positional relationship between the heart and lungs in the different causes of death with regard to age, gender, BMI, cardiomegaly, and lung expansion. MATERIALS: Two hundred fifty consecutive postmortem cases with pre-autopsy PMCT and full forensic autopsy were retrospectively evaluated. The lungs and the mediastinum were manually segmented on the PMCT data and the correspondent volumes were estimated in situ. CTR_VOL was calculated as the ratio of the mediastinal to the thoracic volume. The volume measurements were repeated by the same rater for the evaluation of the intrarater reliability. Age, gender, body weight and height, heart weight at autopsy, and cause of death were retrieved from the autopsy reports. Presence of lung expansion was radiologically evaluated in situ. RESULTS: CTR_VOL was positively associated with age and BMI but not with gender and was higher for cardiomegaly compared to normal hearts, lower for asphyxiation-related deaths compared to cardiac deaths and intoxications, and lower for cases with lung expansion. The intrarater reliability was excellent for the calculated volumes of both lungs and mediastinum. CONCLUSION: The results of the present study support CTR_VOL as a tool to assess the relationship between the heart and lungs in situ, which differs significantly between the studied cause of death categories. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00414-021-02593-0. Springer Berlin Heidelberg 2021-04-28 2021 /pmc/articles/PMC8354949/ /pubmed/33909145 http://dx.doi.org/10.1007/s00414-021-02593-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Chatzaraki, Vasiliki
Ebert, Lars C.
Thali, Michael J.
Haidich, Anna-Bettina
Ampanozi, Garyfalia
Evaluation of the mediastinal-thoracic volume ratio on postmortem computed tomography
title Evaluation of the mediastinal-thoracic volume ratio on postmortem computed tomography
title_full Evaluation of the mediastinal-thoracic volume ratio on postmortem computed tomography
title_fullStr Evaluation of the mediastinal-thoracic volume ratio on postmortem computed tomography
title_full_unstemmed Evaluation of the mediastinal-thoracic volume ratio on postmortem computed tomography
title_short Evaluation of the mediastinal-thoracic volume ratio on postmortem computed tomography
title_sort evaluation of the mediastinal-thoracic volume ratio on postmortem computed tomography
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354949/
https://www.ncbi.nlm.nih.gov/pubmed/33909145
http://dx.doi.org/10.1007/s00414-021-02593-0
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