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False detection of rifampicin resistance using Xpert(®) MTB/RIF Ultra assay due to an A451V mutation in Mycobacterium tuberculosis

BACKGROUND: In a 12 month period, three Irish-born adult cases with pulmonary TB were initially diagnosed by Xpert(®) MTB/RIF Ultra assay, which detected a rifampicin resistance-conferring mutation prompting treatment as potential MDR cases. METHODS: Further laboratory investigations on the cultured...

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Detalles Bibliográficos
Autores principales:	Fitzgibbon, Margaret M, Roycroft, Emma, Sheehan, Gerard, Mc Laughlin, Anne-Marie, Quintyne, Keith Ian, Brabazon, Elaine, O’Meara, Mary, Flanagan, Peter R, Seagar, A -Louise, Laurenson, Ian F, Keane, Joseph, Rogers, Thomas R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355037/ https://www.ncbi.nlm.nih.gov/pubmed/34386770 http://dx.doi.org/10.1093/jacamr/dlab101

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