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Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice
Differences in immune responses to viruses and autoimmune diseases such as systemic lupus erythematosus (SLE) can show sexual dimorphism. Age-associated B cells (ABC) are a population of CD11c(+)T-bet(+) B cells critical for antiviral responses and autoimmune disorders. Absence of DEF6 and SWAP-70,...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355159/ https://www.ncbi.nlm.nih.gov/pubmed/34376664 http://dx.doi.org/10.1038/s41467-021-25102-8 |