Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice

Differences in immune responses to viruses and autoimmune diseases such as systemic lupus erythematosus (SLE) can show sexual dimorphism. Age-associated B cells (ABC) are a population of CD11c(+)T-bet(+) B cells critical for antiviral responses and autoimmune disorders. Absence of DEF6 and SWAP-70,...

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Detalles Bibliográficos
Autores principales: Ricker, Edd, Manni, Michela, Flores-Castro, Danny, Jenkins, Daniel, Gupta, Sanjay, Rivera-Correa, Juan, Meng, Wenzhao, Rosenfeld, Aaron M., Pannellini, Tania, Bachu, Mahesh, Chinenov, Yurii, Sculco, Peter K., Jessberger, Rolf, Prak, Eline T. Luning, Pernis, Alessandra B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355159/
https://www.ncbi.nlm.nih.gov/pubmed/34376664
http://dx.doi.org/10.1038/s41467-021-25102-8

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