Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma

Subclonal genetic heterogeneity and their diverse gene expression impose serious problems in understanding the behavior of cancers and contemplating therapeutic strategies. Here we develop and utilize a capture-based sequencing panel, which covers host hotspot genes and the full-length genome of hum...

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Detalles Bibliográficos
Autores principales: Yamagishi, Makoto, Kubokawa, Miyuki, Kuze, Yuta, Suzuki, Ayako, Yokomizo, Akari, Kobayashi, Seiichiro, Nakashima, Makoto, Makiyama, Junya, Iwanaga, Masako, Fukuda, Takahiro, Watanabe, Toshiki, Suzuki, Yutaka, Uchimaru, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355240/
https://www.ncbi.nlm.nih.gov/pubmed/34376672
http://dx.doi.org/10.1038/s41467-021-25101-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355240/
https://www.ncbi.nlm.nih.gov/pubmed/34376672
http://dx.doi.org/10.1038/s41467-021-25101-9

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