Cargando…

Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma

Subclonal genetic heterogeneity and their diverse gene expression impose serious problems in understanding the behavior of cancers and contemplating therapeutic strategies. Here we develop and utilize a capture-based sequencing panel, which covers host hotspot genes and the full-length genome of hum...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamagishi, Makoto, Kubokawa, Miyuki, Kuze, Yuta, Suzuki, Ayako, Yokomizo, Akari, Kobayashi, Seiichiro, Nakashima, Makoto, Makiyama, Junya, Iwanaga, Masako, Fukuda, Takahiro, Watanabe, Toshiki, Suzuki, Yutaka, Uchimaru, Kaoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355240/ https://www.ncbi.nlm.nih.gov/pubmed/34376672 http://dx.doi.org/10.1038/s41467-021-25101-9

Ejemplares similares

CD4(+)CADM1(+) cell percentage predicts disease progression in HTLV‐1 carriers and indolent adult T‐cell leukemia/lymphoma
por: Makiyama, Junya, et al.
Publicado: (2019)

Clonal Selection and Evolution of HTLV-1-Infected Cells Driven by Genetic and Epigenetic Alteration
por: Yamagishi, Makoto, et al.
Publicado: (2022)

Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1–associated myelopathy/tropical spastic paraparesis
por: Nagasaka, Misako, et al.
Publicado: (2020)

Overexpression of aberrant Wnt5a and its effect on acquisition of malignant phenotypes in adult T-cell leukemia/lymphoma (ATL) cells
por: Nakano, Kazumi, et al.
Publicado: (2021)

HTLV-1-Mediated Epigenetic Pathway to Adult T-Cell Leukemia–Lymphoma
por: Yamagishi, Makoto, et al.
Publicado: (2018)

CD30 Expression and Its Functions during the Disease Progression of Adult T-Cell Leukemia/Lymphoma
por: Nakashima, Makoto, et al.
Publicado: (2023)

The oncogenic driving force of CD30 signaling‐induced chromosomal instability in adult T‐cell leukemia/lymphoma
por: Nakashima, Makoto, et al.
Publicado: (2023)

Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia
por: Takahashi, Ryutaro, et al.
Publicado: (2014)

Progression of adult T‐cell leukemia/lymphoma from smoldering to acute type due to branched subclonal evolution
por: Jimbo, Koji, et al.
Publicado: (2023)

EZH2 dependent epigenetic landscape in adult T cell leukemia and Tax immortalized cells
por: Fujikawa, Dai, et al.
Publicado: (2015)

Differentiation of Hodgkin lymphoma cells by reactive oxygen species and regulation by heme oxygenase‐1 through HIF‐1α
por: Nakashima, Makoto, et al.
Publicado: (2021)

Molecular hallmarks of adult T cell leukemia: miRNA, epigenetics, and emerging signaling abnormalities
por: Yamagishi, Makoto, et al.
Publicado: (2014)

CD30 induces Reed‐Sternberg cell‐like morphology and chromosomal instability in classic Hodgkin lymphoma cell lines
por: Watanabe, Mariko, et al.
Publicado: (2023)

Inferring clonal structure in HTLV-1-infected individuals: towards bridging the gap between analysis and visualization
por: Farmanbar, Amir, et al.
Publicado: (2017)

Epidemiology of adult T‐cell leukemia‐lymphoma in Japan: An updated analysis, 2012‐2013
por: Ito, Shigeki, et al.
Publicado: (2021)

Early hematopoietic stem cell transplantation improve treatment outcome of aggressive ATL.
por: Uchimaru, Kaoru, et al.
Publicado: (2015)

Genetic and epigenetic loss of miR-31 activates NIK-dependent NF-κB pathway in Adult T-cell Leukemia
por: Yamagishi, Makoto, et al.
Publicado: (2011)

Transcriptome analysis of the effect of C-C chemokine receptor 5 deficiency on cell response to Toxoplasma gondii in brain cells
por: Kobayashi, Kaoru, et al.
Publicado: (2019)

Molecular Hallmarks of Adult T Cell Leukemia
por: Yamagishi, Makoto, et al.
Publicado: (2012)

Advanced human T-cell leukemia virus type 1 carriers and early-stage indolent adult T-cell leukemia-lymphoma are indistinguishable based on CADM1 positivity in flow cytometry
por: Kobayashi, Seiichiro, et al.
Publicado: (2015)

Adult T-Cell Leukemia: A Review of Epidemiological Evidence
por: Iwanaga, Masako, et al.
Publicado: (2012)

Disseminated Cryptococcosis with Marked Eosinophilia in a Postpartum Woman
por: Yokoyama, Tetsuya, et al.
Publicado: (2017)

Multidisciplinary insight into clonal expansion of HTLV-1–infected cells in adult T-cell leukemia via modeling by deterministic finite automata coupled with high-throughput sequencing
por: Farmanbar, Amir, et al.
Publicado: (2017)

Prognosis of patients with adult T‐cell leukemia/lymphoma in Japan: A nationwide hospital‐based study
por: Imaizumi, Yoshitaka, et al.
Publicado: (2020)

Transcriptional profiling of Toll-like receptor 2-deficient primary murine brain cells during Toxoplasma gondii infection
por: Umeda, Kousuke, et al.
Publicado: (2017)

EZH1/2 dual inhibitors suppress HTLV-1-infected cell proliferation and hyperimmune response in HTLV-1-associated myelopathy
por: Koseki, Akihito, et al.
Publicado: (2023)

Epidemiological and clinical features of adult T‐cell leukemia–lymphoma in Japan, 2010–2011: A nationwide survey
por: Nosaka, Kisato, et al.
Publicado: (2017)

Consensus and variations in cell line specificity among human metapneumovirus strains
por: Nao, Naganori, et al.
Publicado: (2019)

Measures for the Prevention of Mother-to-Child Human T-Cell Leukemia Virus Type 1 Transmission in Japan: The Burdens of HTLV-1-Infected Mothers
por: Uchimaru, Kaoru, et al.
Publicado: (2023)

Natural History and Chronological Growth Rate of Renal Artery Aneurysms
por: Umetsu, Michihisa, et al.
Publicado: (2017)

Disorders of the cMyb proto-oncogene expression and its significance in the course of ATL development
por: Nakano, Kazumi, et al.
Publicado: (2014)

The role of epigenetics in T-cell lymphoma
por: Yamagishi, Makoto
Publicado: (2022)

Chronology of embryonic and gonadal development in the Reeves’ turtle, Mauremys reevesii
por: Akashi, Hiroshi, et al.
Publicado: (2022)

Single-cell and spatial analyses of cancer cells: toward elucidating the molecular mechanisms of clonal evolution and drug resistance acquisition
por: Nagasawa, Satoi, et al.
Publicado: (2021)

Therapy-related Acute Myeloid Leukemia after the Long-term Administration of Low-dose Etoposide for Chronic-type Adult T-cell Leukemia-lymphoma: A Case Report and Literature Review
por: Shimada, Naoki, et al.
Publicado: (2017)

Role of Autotaxin in High Glucose-Induced Human ARPE-19 Cells
por: Liu, Yang, et al.
Publicado: (2022)

A Nationwide Antenatal Human T-Cell Leukemia Virus Type-1 Antibody Screening in Japan
por: Itabashi, Kazuo, et al.
Publicado: (2020)

Chronology of Anæsthesia
Publicado: (1868)

Immune evasion and chronological decrease in titer of neutralizing antibody against SARS-CoV-2 and its variants of concerns in COVID-19 patients
por: Takeshita, Masaru, et al.
Publicado: (2022)

Changes in postural sway during upright stance after short-term lower limb physical inactivity: A prospective study
por: Ikeda, Takuro, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_v164tkgccebt2o06nhesea7nnv