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Gene delivery to the hypoglossal motor system: preclinical studies and translational potential

Dysfunction and/or reduced activity in the tongue muscles contributes to conditions such as dysphagia, dysarthria, and sleep disordered breathing. Current treatments are often inadequate, and the tongue is a readily accessible target for therapeutic gene delivery. In this regard, gene therapy specif...

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Detalles Bibliográficos
Autores principales: Doyle, Brendan M., Singer, Michele L., Fleury-Curado, Thomaz, Rana, Sabhya, Benevides, Ethan S., Byrne, Barry J., Polotsky, Vsevolod Y., Fuller, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355248/
https://www.ncbi.nlm.nih.gov/pubmed/33574581
http://dx.doi.org/10.1038/s41434-021-00225-1