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Gene delivery to the hypoglossal motor system: preclinical studies and translational potential
Dysfunction and/or reduced activity in the tongue muscles contributes to conditions such as dysphagia, dysarthria, and sleep disordered breathing. Current treatments are often inadequate, and the tongue is a readily accessible target for therapeutic gene delivery. In this regard, gene therapy specif...
Autores principales: | Doyle, Brendan M., Singer, Michele L., Fleury-Curado, Thomaz, Rana, Sabhya, Benevides, Ethan S., Byrne, Barry J., Polotsky, Vsevolod Y., Fuller, David D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355248/ https://www.ncbi.nlm.nih.gov/pubmed/33574581 http://dx.doi.org/10.1038/s41434-021-00225-1 |
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