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Contribution of Energy Dysfunction to Impaired Protein Translation in Neurodegenerative Diseases
Impaired energy homeostasis and aberrant translational control have independently been implicated in the pathogenesis of neurodegenerative diseases. AMP kinase (AMPK), regulated by the ratio of cellular AMP and ATP, is a major gatekeeper for cellular energy homeostasis. Abnormal regulation of AMPK h...
Autores principales: | Liu, Yu-Ju, Chern, Yijuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355359/ https://www.ncbi.nlm.nih.gov/pubmed/34393724 http://dx.doi.org/10.3389/fncel.2021.668500 |
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