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Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts

Gastric cancer (GC) is commonly treated by chemotherapy using 5-fluorouracil (5-FU) derivatives and platinum combination, but predictive biomarker remains lacking. We develop patient-derived xenografts (PDXs) from 31 GC patients and treat with a combination of 5-FU and oxaliplatin, to determine biom...

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Detalles Bibliográficos
Autores principales:	Na, Deukchae, Chae, Jeesoo, Cho, Sung-Yup, Kang, Wonyoung, Lee, Ahra, Min, Seoyeon, Kang, Jinjoo, Kim, Min Jung, Choi, Jaeyong, Lee, Woochan, Shin, Dongjin, Min, Ahrum, Kim, Yu-Jin, Lee, Kyung-Hun, Kim, Tae-Yong, Suh, Yun-Suhk, Kong, Seong-Ho, Lee, Hyuk-Joon, Kim, Woo-Ho, Park, Hansoo, Im, Seock-Ah, Yang, Han-Kwang, Lee, Charles, Kim, Jong-Il
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355375/ https://www.ncbi.nlm.nih.gov/pubmed/34376661 http://dx.doi.org/10.1038/s41467-021-25122-4

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