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Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion
A 67-year-old woman with a history of autoimmune hepatitis was admitted for fever, acute hepatic dysfunction, and acute kidney injury. She was diagnosed with multiple duodenal ulcers. Despite the administration of proton pump inhibitor and red blood cells, her black stool and anemia progressed, and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355396/ https://www.ncbi.nlm.nih.gov/pubmed/33583894 http://dx.doi.org/10.2169/internalmedicine.6463-20 |
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author | Yamada, Yusuke Abe, Tomohiro Ochiai, Hidenobu Ashizuka, Shinya |
author_facet | Yamada, Yusuke Abe, Tomohiro Ochiai, Hidenobu Ashizuka, Shinya |
author_sort | Yamada, Yusuke |
collection | PubMed |
description | A 67-year-old woman with a history of autoimmune hepatitis was admitted for fever, acute hepatic dysfunction, and acute kidney injury. She was diagnosed with multiple duodenal ulcers. Despite the administration of proton pump inhibitor and red blood cells, her black stool and anemia progressed, and she was therefore transferred to our hospital. Despite hemostatic treatments, she continued to bleed. On the 21st day of admission, an endoscopic examination showed the oozing of blood from the duodenal mucosa. A low factor XIII (FXIII) activity level was detected, and she was administered FXIII concentrate. The bleeding stopped and she was thereafter discharged. |
format | Online Article Text |
id | pubmed-8355396 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-83553962021-08-24 Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion Yamada, Yusuke Abe, Tomohiro Ochiai, Hidenobu Ashizuka, Shinya Intern Med Case Report A 67-year-old woman with a history of autoimmune hepatitis was admitted for fever, acute hepatic dysfunction, and acute kidney injury. She was diagnosed with multiple duodenal ulcers. Despite the administration of proton pump inhibitor and red blood cells, her black stool and anemia progressed, and she was therefore transferred to our hospital. Despite hemostatic treatments, she continued to bleed. On the 21st day of admission, an endoscopic examination showed the oozing of blood from the duodenal mucosa. A low factor XIII (FXIII) activity level was detected, and she was administered FXIII concentrate. The bleeding stopped and she was thereafter discharged. The Japanese Society of Internal Medicine 2021-02-15 2021-07-15 /pmc/articles/PMC8355396/ /pubmed/33583894 http://dx.doi.org/10.2169/internalmedicine.6463-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Yamada, Yusuke Abe, Tomohiro Ochiai, Hidenobu Ashizuka, Shinya Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion |
title | Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion |
title_full | Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion |
title_fullStr | Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion |
title_full_unstemmed | Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion |
title_short | Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion |
title_sort | refractory duodenal bleeding ulcers successfully treated with factor xiii transfusion |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355396/ https://www.ncbi.nlm.nih.gov/pubmed/33583894 http://dx.doi.org/10.2169/internalmedicine.6463-20 |
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