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Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion

A 67-year-old woman with a history of autoimmune hepatitis was admitted for fever, acute hepatic dysfunction, and acute kidney injury. She was diagnosed with multiple duodenal ulcers. Despite the administration of proton pump inhibitor and red blood cells, her black stool and anemia progressed, and...

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Detalles Bibliográficos
Autores principales: Yamada, Yusuke, Abe, Tomohiro, Ochiai, Hidenobu, Ashizuka, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355396/
https://www.ncbi.nlm.nih.gov/pubmed/33583894
http://dx.doi.org/10.2169/internalmedicine.6463-20
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author Yamada, Yusuke
Abe, Tomohiro
Ochiai, Hidenobu
Ashizuka, Shinya
author_facet Yamada, Yusuke
Abe, Tomohiro
Ochiai, Hidenobu
Ashizuka, Shinya
author_sort Yamada, Yusuke
collection PubMed
description A 67-year-old woman with a history of autoimmune hepatitis was admitted for fever, acute hepatic dysfunction, and acute kidney injury. She was diagnosed with multiple duodenal ulcers. Despite the administration of proton pump inhibitor and red blood cells, her black stool and anemia progressed, and she was therefore transferred to our hospital. Despite hemostatic treatments, she continued to bleed. On the 21st day of admission, an endoscopic examination showed the oozing of blood from the duodenal mucosa. A low factor XIII (FXIII) activity level was detected, and she was administered FXIII concentrate. The bleeding stopped and she was thereafter discharged.
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spelling pubmed-83553962021-08-24 Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion Yamada, Yusuke Abe, Tomohiro Ochiai, Hidenobu Ashizuka, Shinya Intern Med Case Report A 67-year-old woman with a history of autoimmune hepatitis was admitted for fever, acute hepatic dysfunction, and acute kidney injury. She was diagnosed with multiple duodenal ulcers. Despite the administration of proton pump inhibitor and red blood cells, her black stool and anemia progressed, and she was therefore transferred to our hospital. Despite hemostatic treatments, she continued to bleed. On the 21st day of admission, an endoscopic examination showed the oozing of blood from the duodenal mucosa. A low factor XIII (FXIII) activity level was detected, and she was administered FXIII concentrate. The bleeding stopped and she was thereafter discharged. The Japanese Society of Internal Medicine 2021-02-15 2021-07-15 /pmc/articles/PMC8355396/ /pubmed/33583894 http://dx.doi.org/10.2169/internalmedicine.6463-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yamada, Yusuke
Abe, Tomohiro
Ochiai, Hidenobu
Ashizuka, Shinya
Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion
title Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion
title_full Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion
title_fullStr Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion
title_full_unstemmed Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion
title_short Refractory Duodenal Bleeding Ulcers Successfully Treated with Factor XIII Transfusion
title_sort refractory duodenal bleeding ulcers successfully treated with factor xiii transfusion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355396/
https://www.ncbi.nlm.nih.gov/pubmed/33583894
http://dx.doi.org/10.2169/internalmedicine.6463-20
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