Cargando…

β-Asarone Attenuates Aβ-Induced Neuronal Damage in PC12 Cells Overexpressing APPswe by Restoring Autophagic Flux

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory damage and cognitive dysfunction. Studies have shown that defective autophagic flux is associated with neuronal dysfunction. Modulating autophagic activity represents a potential method of combating AD. In C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zhenwan, Ma, Jin, Kuang, Zhongsheng, Jiang, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355419/ https://www.ncbi.nlm.nih.gov/pubmed/34393783 http://dx.doi.org/10.3389/fphar.2021.701635

Ejemplares similares

β-Asarone Ameliorates β-Amyloid–Induced Neurotoxicity in PC12 Cells by Activating P13K/Akt/Nrf2 Signaling Pathway
por: Meng, Miaomiao, et al.
Publicado: (2021)

β-Asarone Inhibits Amyloid-β by Promoting Autophagy in a Cell Model of Alzheimer's Disease
por: Wang, Nanbu, et al.
Publicado: (2020)

Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development
por: Zhou, Haikang, et al.
Publicado: (2021)

α-Asarone Attenuates Osteoclastogenesis and Prevents Against Oestrogen-Deficiency Induced Osteoporosis
por: Tian, Hao, et al.
Publicado: (2022)

Ubc9 Attenuates Myocardial Ischemic Injury Through Accelerating Autophagic Flux
por: Xiao, Qing, et al.
Publicado: (2020)

BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux
por: Shen, Shuangjun, et al.
Publicado: (2020)

Preclinical evidence and possible mechanisms of β-asarone for rats and mice with Alzheimer’s disease: A systematic review and meta-analysis
por: Du, Xin-Yuan, et al.
Publicado: (2022)

Crocetin attenuates inflammation and amyloid-β accumulation in APPsw transgenic mice
por: Zhang, Jin, et al.
Publicado: (2018)

Effect of β-asarone in normal and β-amyloid-induced Alzheimeric rats
por: Saki, Golshid, et al.
Publicado: (2020)

Iron Promotes Dihydroartemisinin Cytotoxicity via ROS Production and Blockade of Autophagic Flux via Lysosomal Damage in Osteosarcoma
por: Shen, Ying, et al.
Publicado: (2020)

Fate of β-asarone in Ayurvedic Sodhana process of Vacha
por: Gholkar, Manasi S., et al.
Publicado: (2013)

β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells
por: Jalal, Sajid, et al.
Publicado: (2022)

Berberine Ameliorates High Glucose-Induced Cardiomyocyte Injury via AMPK Signaling Activation to Stimulate Mitochondrial Biogenesis and Restore Autophagic Flux
por: Hang, Weijian, et al.
Publicado: (2018)

Hepatotoxic potential of asarones: in vitro evaluation of hepatotoxicity and quantitative determination in herbal products
por: Patel, Dhavalkumar N., et al.
Publicado: (2015)

Nitro Derivatives of Naturally Occurring β-Asarone and Their Anticancer Activity
por: Shenvi, Suvarna, et al.
Publicado: (2014)

Gintonin stimulates autophagic flux in primary cortical astrocytes
por: Rahman, Md. Ataur, et al.
Publicado: (2020)

Synergetic effect of β-asarone and cannabidiol against Aβ aggregation in vitro and in vivo
por: Duan, Fangyuan, et al.
Publicado: (2023)

Oral Administration of α-Asarone Promotes Functional Recovery in Rats With Spinal Cord Injury
por: Jo, Min-Jae, et al.
Publicado: (2018)

ox-LDL induces autophagy-mediated apoptosis by suppressing secretagogin-regulated autophagic flux in pancreatic β-cells: SCGN regulates autophagic flux in β-cells
por: Lv, Ying, et al.
Publicado: (2022)

Lactobacillus rhamnosus attenuates intestinal inflammation induced by Fusobacterium nucleatum infection by restoring the autophagic flux
por: Duan, Caihan, et al.
Publicado: (2021)

Acylated Ghrelin is Protective Against 6-OHDA-induced Neurotoxicity by Regulating Autophagic Flux
por: He, Xin, et al.
Publicado: (2021)

β-Asarone Increases Chemosensitivity by Inhibiting Tumor Glycolysis in Gastric Cancer
por: Tao, Heyun, et al.
Publicado: (2020)

Corrigendum: Oral Administration of α-Asarone Promotes Functional Recovery in Rats With Spinal Cord Injury
por: Jo, Min-Jae, et al.
Publicado: (2018)

Corilagin Alleviates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced C57BL/6 Mice by Ameliorating Oxidative Stress and Restoring Autophagic Flux
por: Zhang, Rong, et al.
Publicado: (2020)

Hydrogen Sulfide Attenuates β2-Microglobulin-Induced Cognitive Dysfunction: Involving Recovery of Hippocampal Autophagic Flux
por: Chen, Si-Min, et al.
Publicado: (2019)

Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration
por: Kang, Liang, et al.
Publicado: (2019)

β-Asarone Rescues Pb-Induced Impairments of Spatial Memory and Synaptogenesis in Rats
por: Yang, Qian-Qian, et al.
Publicado: (2016)

Molecular Mechanisms and Therapeutic Potential of α- and β-Asarone in the Treatment of Neurological Disorders
por: Balakrishnan, Rengasamy, et al.
Publicado: (2022)

Explore the Mechanism of β-Asarone on Improving Cognitive Dysfunction in Rats with Diabetic Encephalopathy
por: Cai, Jingwen, et al.
Publicado: (2022)

Neuroprotective Effects and Mechanism of β-Asarone against Aβ1–42-Induced Injury in Astrocytes
por: Yang, Yuanxiao, et al.
Publicado: (2017)

Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux
por: Wang, Dong, et al.
Publicado: (2019)

Identification of both GABA(A) receptors and voltage-activated Na(+) channels as molecular targets of anticonvulsant α-asarone
por: Wang, Ze-Jun, et al.
Publicado: (2014)

Autophagic flux modulation by Wnt/β-catenin pathway inhibition in hepatocellular carcinoma
por: Turcios, Lilia, et al.
Publicado: (2019)

Melatonin Restores Autophagic Flux by Activating the Sirt3/TFEB Signaling Pathway to Attenuate Doxorubicin-Induced Cardiomyopathy
por: Ma, Yanyan, et al.
Publicado: (2023)

9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice
por: Wang, Yan-Mei, et al.
Publicado: (2021)

Celecoxib alleviates nonalcoholic fatty liver disease by restoring autophagic flux
por: Liu, Cong, et al.
Publicado: (2018)

Autophagic flux restoration enhances the antitumor efficacy of tumor infiltrating lymphocytes
por: Zhang, Chaoting, et al.
Publicado: (2022)

β-Asarone Protects PC12 Cells Against Hypoxia-Induced Injury Via Negatively Regulating RPPH1/MiR-542-3p/DEDD2 Axis
por: Yang, Fan, et al.
Publicado: (2022)

Transgenic Overexpression of Galectin-3 in Pancreatic β Cells Attenuates Hyperglycemia in Mice: Synergistic Antidiabetic Effect With Exogenous IL-33
por: Jovicic, Nemanja, et al.
Publicado: (2021)

Corrigendum: 9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice
por: Wang, Yan-Mei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_l869m905i25nj2jcmg9mg43cij