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Like Wings of a Bird: Functional Divergence and Complementarity between HLA-A and HLA-B Molecules

Human leukocyte antigen (HLA) genes are among the most polymorphic of our genome, as a likely consequence of balancing selection related to their central role in adaptive immunity. HLA-A and HLA-B genes were recently suggested to evolve through a model of joint divergent asymmetric selection conferr...

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Detalles Bibliográficos
Autores principales: Di, Da, Nunes, Jose Manuel, Jiang, Wei, Sanchez-Mazas, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355449/
https://www.ncbi.nlm.nih.gov/pubmed/33320202
http://dx.doi.org/10.1093/molbev/msaa325