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Like Wings of a Bird: Functional Divergence and Complementarity between HLA-A and HLA-B Molecules
Human leukocyte antigen (HLA) genes are among the most polymorphic of our genome, as a likely consequence of balancing selection related to their central role in adaptive immunity. HLA-A and HLA-B genes were recently suggested to evolve through a model of joint divergent asymmetric selection conferr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355449/ https://www.ncbi.nlm.nih.gov/pubmed/33320202 http://dx.doi.org/10.1093/molbev/msaa325 |