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Supraspinatus Rotator Cuff Repair: A Mouse Model and Technique

To improve understanding of the pathophysiology of rotator cuff repair and develop therapeutic treatments an animal model is essential. This Technical Note describes a comprehensive step-by-step description of rotator cuff repair in the mouse. This technique is particularly beneficial because the mu...

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Autores principales: Miller, Matthew, Kazmers, Nikolas H., Chalmers, Peter N., Tashjian, Robert Z., Jurynec, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355505/
https://www.ncbi.nlm.nih.gov/pubmed/34401238
http://dx.doi.org/10.1016/j.eats.2021.04.023
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author Miller, Matthew
Kazmers, Nikolas H.
Chalmers, Peter N.
Tashjian, Robert Z.
Jurynec, Michael J.
author_facet Miller, Matthew
Kazmers, Nikolas H.
Chalmers, Peter N.
Tashjian, Robert Z.
Jurynec, Michael J.
author_sort Miller, Matthew
collection PubMed
description To improve understanding of the pathophysiology of rotator cuff repair and develop therapeutic treatments an animal model is essential. This Technical Note describes a comprehensive step-by-step description of rotator cuff repair in the mouse. This technique is particularly beneficial because the murine rotator cuff is anatomically similar to that of humans. The mouse model can also be used to test the biological role of candidate genes during repair and be used to identify drugs that accelerate the healing process.
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spelling pubmed-83555052021-08-15 Supraspinatus Rotator Cuff Repair: A Mouse Model and Technique Miller, Matthew Kazmers, Nikolas H. Chalmers, Peter N. Tashjian, Robert Z. Jurynec, Michael J. Arthrosc Tech Technical Note To improve understanding of the pathophysiology of rotator cuff repair and develop therapeutic treatments an animal model is essential. This Technical Note describes a comprehensive step-by-step description of rotator cuff repair in the mouse. This technique is particularly beneficial because the murine rotator cuff is anatomically similar to that of humans. The mouse model can also be used to test the biological role of candidate genes during repair and be used to identify drugs that accelerate the healing process. Elsevier 2021-07-13 /pmc/articles/PMC8355505/ /pubmed/34401238 http://dx.doi.org/10.1016/j.eats.2021.04.023 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Technical Note
Miller, Matthew
Kazmers, Nikolas H.
Chalmers, Peter N.
Tashjian, Robert Z.
Jurynec, Michael J.
Supraspinatus Rotator Cuff Repair: A Mouse Model and Technique
title Supraspinatus Rotator Cuff Repair: A Mouse Model and Technique
title_full Supraspinatus Rotator Cuff Repair: A Mouse Model and Technique
title_fullStr Supraspinatus Rotator Cuff Repair: A Mouse Model and Technique
title_full_unstemmed Supraspinatus Rotator Cuff Repair: A Mouse Model and Technique
title_short Supraspinatus Rotator Cuff Repair: A Mouse Model and Technique
title_sort supraspinatus rotator cuff repair: a mouse model and technique
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355505/
https://www.ncbi.nlm.nih.gov/pubmed/34401238
http://dx.doi.org/10.1016/j.eats.2021.04.023
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