Decreased inhibition of exosomal miRNAs on SARS-CoV-2 replication underlies poor outcomes in elderly people and diabetic patients

Elderly people and patients with comorbidities are at higher risk of COVID-19 infection, resulting in severe complications and high mortality. However, the underlying mechanisms are unclear. In this study, we investigate whether miRNAs in serum exosomes can exert antiviral functions and affect the r...

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Detalles Bibliográficos
Autores principales: Wang, Yanbo, Zhu, Xiaoju, Jiang, Xia-Ming, Guo, Jingwei, Fu, Zheng, Zhou, Zhen, Yang, Ping, Guo, Hongyuan, Guo, Xu, Liang, Gaoli, Zeng, Ping, Xiao, Gengfu, Ma, Jizheng, Yin, Xin, Zhang, Lei-Ke, Yan, Chao, Zhang, Chen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355568/
https://www.ncbi.nlm.nih.gov/pubmed/34381015
http://dx.doi.org/10.1038/s41392-021-00716-y

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