Functions and Diseases of the Retinal Pigment Epithelium

The retinal pigment epithelium is a fundamental component of the retina that plays essential roles in visual functions. Damage to the structure and function of the retinal pigment epithelium leads to a variety of retinopathies, and there is currently no curative therapy for these disorders. Therefor...

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Autores principales: Yang, Song, Zhou, Jun, Li, Dengwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355697/
https://www.ncbi.nlm.nih.gov/pubmed/34393803
http://dx.doi.org/10.3389/fphar.2021.727870
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author Yang, Song
Zhou, Jun
Li, Dengwen
author_facet Yang, Song
Zhou, Jun
Li, Dengwen
author_sort Yang, Song
collection PubMed
description The retinal pigment epithelium is a fundamental component of the retina that plays essential roles in visual functions. Damage to the structure and function of the retinal pigment epithelium leads to a variety of retinopathies, and there is currently no curative therapy for these disorders. Therefore, studying the relationship between the development, function, and pathobiology of the retinal pigment epithelium is important for the prevention and treatment of retinopathies. Here we review the function of the retinal pigment epithelium and its relevance to the pathobiology, and discuss potential strategies for the treatment of retinopathies. In doing so, we provide new viewpoints outlining new ideas for the future study and treatment of retinopathies.
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spelling pubmed-83556972021-08-12 Functions and Diseases of the Retinal Pigment Epithelium Yang, Song Zhou, Jun Li, Dengwen Front Pharmacol Pharmacology The retinal pigment epithelium is a fundamental component of the retina that plays essential roles in visual functions. Damage to the structure and function of the retinal pigment epithelium leads to a variety of retinopathies, and there is currently no curative therapy for these disorders. Therefore, studying the relationship between the development, function, and pathobiology of the retinal pigment epithelium is important for the prevention and treatment of retinopathies. Here we review the function of the retinal pigment epithelium and its relevance to the pathobiology, and discuss potential strategies for the treatment of retinopathies. In doing so, we provide new viewpoints outlining new ideas for the future study and treatment of retinopathies. Frontiers Media S.A. 2021-07-28 /pmc/articles/PMC8355697/ /pubmed/34393803 http://dx.doi.org/10.3389/fphar.2021.727870 Text en Copyright © 2021 Yang, Zhou and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Yang, Song
Zhou, Jun
Li, Dengwen
Functions and Diseases of the Retinal Pigment Epithelium
title Functions and Diseases of the Retinal Pigment Epithelium
title_full Functions and Diseases of the Retinal Pigment Epithelium
title_fullStr Functions and Diseases of the Retinal Pigment Epithelium
title_full_unstemmed Functions and Diseases of the Retinal Pigment Epithelium
title_short Functions and Diseases of the Retinal Pigment Epithelium
title_sort functions and diseases of the retinal pigment epithelium
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355697/
https://www.ncbi.nlm.nih.gov/pubmed/34393803
http://dx.doi.org/10.3389/fphar.2021.727870
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AT zhoujun functionsanddiseasesoftheretinalpigmentepithelium
AT lidengwen functionsanddiseasesoftheretinalpigmentepithelium

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