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CK-3, A Novel Methsulfonyl Pyridine Derivative, Suppresses Hepatocellular Carcinoma Proliferation and Invasion by Blocking the PI3K/AKT/mTOR and MAPK/ERK Pathways

Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor prognosis that highly expresses phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (ERK). The PI3K/AKT/mTOR and MAPK/ERK signaling pathways play a crucial role in HCC tumor formation, cell cycle, apoptosis and s...

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Detalles Bibliográficos
Autores principales:	Wu, Qiong, Liu, Tian-yi, Hu, Bai-chun, Li, Xiang, Wu, Yu-ting, Sun, Xiao-tong, Jiang, Xiao-wen, Wang, Shu, Qin, Xiao-chun, Ding, Huai-wei, Zhao, Qing-chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355706/ https://www.ncbi.nlm.nih.gov/pubmed/34395292 http://dx.doi.org/10.3389/fonc.2021.717626

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