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Ursolic Acid Loaded-Mesoporous Hydroxylapatite/ Chitosan Therapeutic Scaffolds Regulate Bone Regeneration Ability by Promoting the M2-Type Polarization of Macrophages

PURPOSE: Mesoporous hydroxylapatite (MHAP) might be important for bone regeneration, and ursolic acid (UA) has anti-inflammatory effects. Accordingly, we developed, for the first time, ursolic acid-loaded MHAP-chitosan (MHAP-CS-UA) scaffolds to treat bone defects. METHODS: In vitro, we synthesize bi...

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Detalles Bibliográficos
Autores principales:	Yu, Xijiao, Wang, Yuxuan, Liu, Xiaoliang, Ge, Yuwei, Zhang, Shanyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355748/ https://www.ncbi.nlm.nih.gov/pubmed/34393482 http://dx.doi.org/10.2147/IJN.S323033

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