Cargando…

ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells

BACKGROUND: Vitamin D receptor (VDR) plays a vital protective role in oral and colonic epithelial cells. Albeit we know that VDR expression is reduced in the mucosal epithelial layers of autoimmune diseases, the mechanism by which VDR is decreased remains elusive. METHODS: VDR and zinc finger protei...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiangyu, Ge, Xuejun, Liao, Wang, Cao, Yong, Li, Ran, Zhang, Fang, Zhao, Bin, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355874/
https://www.ncbi.nlm.nih.gov/pubmed/34380509
http://dx.doi.org/10.1186/s12964-021-00765-4