A case report of blastic plasmacytoid dendritic cell neoplasm in a hispanic child

Plasmacytoid dendritic cell neoplasms are aggressive and rare hematologic malignancies characterized by clonal expansion of plasmacytoid dendritic cells with frequent cutaneous involvement. The pathogenesis is not well established, and it shows enhanced expression of CD56, CD4 and CD123 detected by...

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Detalles Bibliográficos
Autores principales: Tanchiva, Katy Ordoñez, Chavez, Pamela Contreras, Guevara, Silvana Lucero Loli, Vicuña, Carlos Rodrigo Quispe, Bhardwaj, Neharika, Lansigan, Frederick, Deconinck, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355953/
https://www.ncbi.nlm.nih.gov/pubmed/34401319
http://dx.doi.org/10.1016/j.lrr.2021.100262
Descripción
Sumario:Plasmacytoid dendritic cell neoplasms are aggressive and rare hematologic malignancies characterized by clonal expansion of plasmacytoid dendritic cells with frequent cutaneous involvement. The pathogenesis is not well established, and it shows enhanced expression of CD56, CD4 and CD123 detected by flow cytometry and immunohistochemistry. We report a case report of this rare disease in a hispanic child with complete remission after using a protocol for high-risk acute lymphoblastic leukemia.

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