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Cytopathic effects and local immune responses in repeated neoadjuvant HSV-tk + ganciclovir gene therapy for prostate cancer

OBJECTIVE: Cytopathic effects and local immune response were analyzed histologically in prostatic cancer (PCa) with in situ herpes simplex virus-thymidine kinase (HSV-tk)/ganciclovir (GCV) gene therapy (GT). METHODS: Four high-risk PCa patients who received HSV-tk/GCV GT were investigated. After two...

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Detalles Bibliográficos
Autores principales:	Yanagisawa, Nobuyuki, Satoh, Takefumi, Tabata, Ken-ichi, Tsumura, Hideyasu, Nasu, Yasutomo, Watanabe, Masami, Thompson, Timothy C., Okayasu, Isao, Murakumo, Yoshiki, Baba, Shiro, Iwamura, Masatsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Second Military Medical University 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356062/ https://www.ncbi.nlm.nih.gov/pubmed/34401335 http://dx.doi.org/10.1016/j.ajur.2020.06.004

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