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Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial
BACKGROUND: Ceftolozane/tazobactam is approved for treatment of hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP) at double the dose approved for other infection sites. Among nosocomial pneumonia subtypes, ventilated HABP (vHABP) is associated with the lowest survival. In the A...
Autores principales: | Timsit, Jean-François, Huntington, Jennifer A., Wunderink, Richard G., Shime, Nobuaki, Kollef, Marin H., Kivistik, Ülo, Nováček, Martin, Réa-Neto, Álvaro, Martin-Loeches, Ignacio, Yu, Brian, Jensen, Erin H., Butterton, Joan R., Wolf, Dominik J., Rhee, Elizabeth G., Bruno, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356211/ https://www.ncbi.nlm.nih.gov/pubmed/34380538 http://dx.doi.org/10.1186/s13054-021-03694-3 |
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