Comparison of iguratimod and conventional cyclophosphamide with sequential azathioprine as treatment of active lupus nephritis: study protocol for a multi-center, randomized, controlled clinical trial (iGeLU study)

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease that can involve multiple organs or systems. Lupus nephritis (LN) is associated with high mortality and morbidity. However, plenty of patients do not respond to present treatment or relapse. Iguratimod (IGU) is a new small molec...

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Detalles Bibliográficos
Autores principales: Yan, Qingran, Du, Fang, Kang, Yuening, Ye, Ping, Wang, Xiaodong, Xu, Jianhua, Tang, Jianping, Wang, Niansong, Jiang, Gengru, Li, Zhijun, Wang, Xuan, Xue, Qin, Huang, Xinfang, Zhang, Xiaoyan, Zhou, Ying, Dai, Min, Bao, Chunde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356213/
https://www.ncbi.nlm.nih.gov/pubmed/34380536
http://dx.doi.org/10.1186/s13063-021-05475-3

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