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Human umbilical cord mesenchymal stem cells reduce oxidative damage and apoptosis in diabetic nephropathy by activating Nrf2

BACKGROUND: Mesenchymal stem cells (MSCs) have a therapeutic effect on diabetic nephropathy (DN) but the underlying mechanism remains unclear. This study was conducted to investigate whether human umbilical cord-MSCs (hUCMSCs) can induce oxidative damage and apoptosis by activating Nrf2. METHODS: We...

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Detalles Bibliográficos
Autores principales: Nie, Ping, Bai, Xue, Lou, Yan, Zhu, Yuexin, Jiang, Shan, Zhang, Lina, Tian, Na, Luo, Ping, Li, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356418/
https://www.ncbi.nlm.nih.gov/pubmed/34380544
http://dx.doi.org/10.1186/s13287-021-02447-x