Cargando…

Human umbilical cord mesenchymal stem cells reduce oxidative damage and apoptosis in diabetic nephropathy by activating Nrf2

BACKGROUND: Mesenchymal stem cells (MSCs) have a therapeutic effect on diabetic nephropathy (DN) but the underlying mechanism remains unclear. This study was conducted to investigate whether human umbilical cord-MSCs (hUCMSCs) can induce oxidative damage and apoptosis by activating Nrf2. METHODS: We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nie, Ping, Bai, Xue, Lou, Yan, Zhu, Yuexin, Jiang, Shan, Zhang, Lina, Tian, Na, Luo, Ping, Li, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356418/ https://www.ncbi.nlm.nih.gov/pubmed/34380544 http://dx.doi.org/10.1186/s13287-021-02447-x

Ejemplares similares

Influence of zinc levels and Nrf2 expression in the clinical and pathological changes in patients with diabetic nephropathy
por: Nie, Ping, et al.
Publicado: (2022)

Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorate Nephrocyte Injury and Proteinuria in a Diabetic Nephropathy Rat Model
por: Chen, Lian, et al.
Publicado: (2020)

Human umbilical cord mesenchymal stem cell transplantation restores damaged ovaries
por: Zhu, Shao-Fang, et al.
Publicado: (2015)

Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis
por: Xiang, E, et al.
Publicado: (2020)

Mechanism and therapeutic effect of umbilical cord mesenchymal stem cells in inflammatory bowel disease
por: Pan, Xing-hua, et al.
Publicado: (2019)

Human amnion tissue injected with human umbilical cord mesenchymal stem cells repairs damaged sciatic nerves in rats★
por: Li, Dehua, et al.
Publicado: (2012)

Potential of human umbilical cord blood mesenchymal stem cells to heal damaged corneal endothelium
por: Joyce, Nancy C., et al.
Publicado: (2012)

Human Umbilical Cord Mesenchymal Stem Cells Infected with Adenovirus Expressing HGF Promote Regeneration of Damaged Neuron Cells in a Parkinson's Disease Model
por: Liu, Xin-Shan, et al.
Publicado: (2014)

Therapeutic efficacy of neural stem cells originating from umbilical cord-derived mesenchymal stem cells in diabetic retinopathy
por: Zhang, Wei, et al.
Publicado: (2017)

Umbilical Cord-Derived Mesenchymal Stem Cells for Hematopoietic Stem Cell Transplantation
por: Chao, Yu-Hua, et al.
Publicado: (2012)

Lack of tumorigenesis and protumorigenic activity of human umbilical cord mesenchymal stem cells in NOD SCID mice
por: He, Jie, et al.
Publicado: (2022)

Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis
por: Liu, Yanying, et al.
Publicado: (2010)

Protective effects of human umbilical cord mesenchymal stem cell-derived conditioned medium on ovarian damage
por: Hong, Liming, et al.
Publicado: (2019)

Effect and mechanism of human umbilical cord mesenchymal stem cells in treating allergic rhinitis in mice
por: Kan, Xiao-li, et al.
Publicado: (2020)

Therapeutic potential of conditioned medium obtained from deferoxamine preconditioned umbilical cord mesenchymal stem cells on diabetic nephropathy model
por: Ozkan, Serbay, et al.
Publicado: (2022)

Immunomodulatory Activity of Mesenchymal Stem Cells in Lupus Nephritis: Advances and Applications
por: Li, Jicui, et al.
Publicado: (2022)

Human umbilical cord-derived mesenchymal stem cells reduce monosodium iodoacetate-induced apoptosis in cartilage
por: Chang, Yu-Hsun, et al.
Publicado: (2018)

Umbilical cord mesenchymal stem cells relieve osteoarthritis in rats through immunoregulation and inhibition of chondrocyte apoptosis
por: Pan, Xin, et al.
Publicado: (2023)

Human umbilical cord mesenchymal stem cell-derived exosomes improve ovarian function in natural aging by inhibiting apoptosis
por: Li, Zhongkang, et al.
Publicado: (2023)

Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upregulating MMPs in Mesangial Cells
por: Li, Hongde, et al.
Publicado: (2020)

Exosomes derived from human umbilical cord mesenchymal stem cells alleviate Parkinson’s disease and neuronal damage through inhibition of microglia
por: Zhang, Zhong-Xia, et al.
Publicado: (2023)

Functional characterization of human umbilical cord-derived mesenchymal stem cells for treatment of systolic heart failure
por: Fang, Zhihua, et al.
Publicado: (2016)

Umbilical cord extracts improve diabetic abnormalities in bone marrow-derived mesenchymal stem cells and increase their therapeutic effects on diabetic nephropathy
por: Nagaishi, Kanna, et al.
Publicado: (2017)

Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells
por: Feng, Li-Xin, et al.
Publicado: (2020)

Anti-oxidative effect of zinc in human umbilical cord mesenchymal stem cells
por: Lu, Xiaodan, et al.
Publicado: (2021)

Human umbilical cord mesenchymal stem cells ameliorate acute liver failure by inhibiting apoptosis, inflammation and pyroptosis
por: Liu, Mengting, et al.
Publicado: (2021)

Human umbilical cord mesenchymal stromal cells in regenerative medicine
por: Detamore, Michael S
Publicado: (2013)

Mitochondrial activity of human umbilical cord mesenchymal stem cells
por: Cozene, Blaise M., et al.
Publicado: (2021)

Umbilical Cord Mesenchymal Stromal Cells for Cartilage Regeneration Applications
por: Russo, E., et al.
Publicado: (2022)

Umbilical cord mesenchymal stromal cells—from bench to bedside
por: Chetty, Shashank, et al.
Publicado: (2022)

Transplantation of human cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells in autism
por: Lv, Yong-Tao, et al.
Publicado: (2013)

Glycemic control by umbilical cord-derived mesenchymal stem cells promotes effects of fasting-mimicking diet on type 2 diabetic mice
por: Zhao, Na, et al.
Publicado: (2021)

Human umbilical cord-derived mesenchymal stromal cells ameliorate aging-associated skeletal muscle atrophy and dysfunction by modulating apoptosis and mitochondrial damage in SAMP10 mice
por: Piao, Limei, et al.
Publicado: (2022)

Therapeutic Potential of Umbilical Cord Mesenchymal Stromal Cells Transplantation for Cerebral Palsy: A Case Report
por: Wang, Liming, et al.
Publicado: (2013)

Umbilical Cord Tissue-Derived Mesenchymal Stem Cells Induce T Lymphocyte Apoptosis and Cell Cycle Arrest by Expression of Indoleamine 2, 3-Dioxygenase
por: Li, Xiuying, et al.
Publicado: (2016)

Intranasal administration of Cytoglobin modifies human umbilical cord-derived mesenchymal stem cells and improves hypoxic-ischemia brain damage in neonatal rats by modulating p38 MAPK signaling-mediated apoptosis
por: Yang, Hanhua, et al.
Publicado: (2020)

Umbilical Cord-Derived Mesenchymal Stromal Cells Contribute to Neuroprotection in Neonatal Cortical Neurons Damaged by Oxygen-Glucose Deprivation
por: Mukai, Takeo, et al.
Publicado: (2018)

Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Treat Cutaneous Nerve Damage and Promote Wound Healing
por: Zhu, Ziying, et al.
Publicado: (2022)

Evaluation of the Curative Effect of Umbilical Cord Mesenchymal Stem Cell Therapy for Knee Arthritis in Dogs Using Imaging Technology
por: Zhang, Bei-ying, et al.
Publicado: (2018)

Comparison of human amniotic fluid-derived and umbilical cord Wharton's Jelly-derived mesenchymal stromal cells: Characterization and myocardial differentiation capacity
por: Bai, Jing, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_9kek5e4n9uecomd8el2gql0vuh