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Role of ultrasound in the diagnosis of primary and recurrent dermatofibrosarcoma protuberans
BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is a rare, low- to intermediate-grade sarcoma, which represents a diagnostic imaging challenge. This study aimed to analyze the clinical and ultrasound features of primary and recurrent DFSP to improve the diagnosis. METHODS: Clinical, imaging, and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356448/ https://www.ncbi.nlm.nih.gov/pubmed/34376150 http://dx.doi.org/10.1186/s12885-021-08476-2 |
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author | Zou, Min-Hong Huang, Qing Yang, Ting Jiang, Ye Zhang, Luan-jing Xie, Yang Zheng, Rong-Qin |
author_facet | Zou, Min-Hong Huang, Qing Yang, Ting Jiang, Ye Zhang, Luan-jing Xie, Yang Zheng, Rong-Qin |
author_sort | Zou, Min-Hong |
collection | PubMed |
description | BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is a rare, low- to intermediate-grade sarcoma, which represents a diagnostic imaging challenge. This study aimed to analyze the clinical and ultrasound features of primary and recurrent DFSP to improve the diagnosis. METHODS: Clinical, imaging, and pathological data from a total of 58 patients (23 patients with primary DFSP and 35 patients with recurrent DFSP) were retrospectively reviewed. RESULTS: There was no statistically significant difference in age, sex, tumor size, or echogenicity between the two groups. Most of the primary DFSP lesions involved the overlying dermis and hypodermis, while most of the recurrent DFSP lesions were fixated to more deeply seated structures at the original surgical incision. Red nodules on the skin were found more frequently in the primary group. There were statistically significant differences in the type of lesion and ultrasound tumor morphology (p < 0.050). The lesions in the primary group showed more tentacle-like projections or a “claw” sign, while the lesions in the recurrent group were more commonly oval, lobulated, and irregularly shaped. Hypervascularity was common in both groups. CONCLUSIONS: For primary DFSP, a slow-growing, red nodule on the skin involving the overlying dermis and hypodermis, more frequently a hypoechoic mass with tentacle-like projections or a “claw” sign, was observed. For recurrent DFSP, palpable subcutaneous nodules or subcutaneous masses at the original surgical incision and oval, lobulated, and irregularly shaped lesions were more commonly observed. This may be useful for improving diagnostic accuracy. |
format | Online Article Text |
id | pubmed-8356448 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-83564482021-08-11 Role of ultrasound in the diagnosis of primary and recurrent dermatofibrosarcoma protuberans Zou, Min-Hong Huang, Qing Yang, Ting Jiang, Ye Zhang, Luan-jing Xie, Yang Zheng, Rong-Qin BMC Cancer Research BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is a rare, low- to intermediate-grade sarcoma, which represents a diagnostic imaging challenge. This study aimed to analyze the clinical and ultrasound features of primary and recurrent DFSP to improve the diagnosis. METHODS: Clinical, imaging, and pathological data from a total of 58 patients (23 patients with primary DFSP and 35 patients with recurrent DFSP) were retrospectively reviewed. RESULTS: There was no statistically significant difference in age, sex, tumor size, or echogenicity between the two groups. Most of the primary DFSP lesions involved the overlying dermis and hypodermis, while most of the recurrent DFSP lesions were fixated to more deeply seated structures at the original surgical incision. Red nodules on the skin were found more frequently in the primary group. There were statistically significant differences in the type of lesion and ultrasound tumor morphology (p < 0.050). The lesions in the primary group showed more tentacle-like projections or a “claw” sign, while the lesions in the recurrent group were more commonly oval, lobulated, and irregularly shaped. Hypervascularity was common in both groups. CONCLUSIONS: For primary DFSP, a slow-growing, red nodule on the skin involving the overlying dermis and hypodermis, more frequently a hypoechoic mass with tentacle-like projections or a “claw” sign, was observed. For recurrent DFSP, palpable subcutaneous nodules or subcutaneous masses at the original surgical incision and oval, lobulated, and irregularly shaped lesions were more commonly observed. This may be useful for improving diagnostic accuracy. BioMed Central 2021-08-10 /pmc/articles/PMC8356448/ /pubmed/34376150 http://dx.doi.org/10.1186/s12885-021-08476-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Zou, Min-Hong Huang, Qing Yang, Ting Jiang, Ye Zhang, Luan-jing Xie, Yang Zheng, Rong-Qin Role of ultrasound in the diagnosis of primary and recurrent dermatofibrosarcoma protuberans |
title | Role of ultrasound in the diagnosis of primary and recurrent dermatofibrosarcoma protuberans |
title_full | Role of ultrasound in the diagnosis of primary and recurrent dermatofibrosarcoma protuberans |
title_fullStr | Role of ultrasound in the diagnosis of primary and recurrent dermatofibrosarcoma protuberans |
title_full_unstemmed | Role of ultrasound in the diagnosis of primary and recurrent dermatofibrosarcoma protuberans |
title_short | Role of ultrasound in the diagnosis of primary and recurrent dermatofibrosarcoma protuberans |
title_sort | role of ultrasound in the diagnosis of primary and recurrent dermatofibrosarcoma protuberans |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356448/ https://www.ncbi.nlm.nih.gov/pubmed/34376150 http://dx.doi.org/10.1186/s12885-021-08476-2 |
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