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MAAPER: model-based analysis of alternative polyadenylation using 3′ end-linked reads
Most eukaryotic genes express alternative polyadenylation (APA) isoforms. A growing number of RNA sequencing methods, especially those used for single-cell transcriptome analysis, generate reads close to the polyadenylation site (PAS), termed nearSite reads, hence inherently containing information a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356463/ https://www.ncbi.nlm.nih.gov/pubmed/34376236 http://dx.doi.org/10.1186/s13059-021-02429-5 |