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Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders
OBJECTIVE: Tonsil/adenoidectomy (T/A) is a commonly performed procedure with an average post‐tonsillectomy bleed (PTB) rate between 3 and 5%. Patients with bleeding disorders (BDs) are believed to have an increased risk of PTB. We hypothesize that our medical management of BD patients using a combin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356851/ https://www.ncbi.nlm.nih.gov/pubmed/34401515 http://dx.doi.org/10.1002/lio2.589 |
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author | Pai, Kavya Desai, Harsh Stein, Dagmar Cole, Stephanie |
author_facet | Pai, Kavya Desai, Harsh Stein, Dagmar Cole, Stephanie |
author_sort | Pai, Kavya |
collection | PubMed |
description | OBJECTIVE: Tonsil/adenoidectomy (T/A) is a commonly performed procedure with an average post‐tonsillectomy bleed (PTB) rate between 3 and 5%. Patients with bleeding disorders (BDs) are believed to have an increased risk of PTB. We hypothesize that our medical management of BD patients using a combination of DDAVP/antifibrinolytic agents has a similar PTB rate to control patients. This study suggests a standardized protocol for patients with BDs to avoid PTB. METHODS: A retrospective cohort study was completed for patients with BD who underwent tonsillectomy or T/A at Promedica Toledo or Flower Hospital between 2013 and 2020. Exclusion criteria included incomplete records, diagnosis of BD after surgery, and inability to find age and sex matched control. We defined the control group as patients who underwent T/A without BD. The following variables were collected: age, sex, medical history, BD severity, medications, type of surgery, indication for surgery, estimated blood loss (EBL), pre/postoperative medications, PTB status, and post‐PTB intervention. RESULTS: A total of 164 patient charts were reviewed. There were 82 patients in both cohorts. The BDs represented were platelet function disorder (80.5%), von Willebrand disease (14.6%), and others such as Factor VII and IX deficiency (4.9%). Of the BD patients included, 13.4% had severe disease. There was no significant difference between the age, sex, EBL, and PTB rates. Of the 8 BD patients with PTB, 62% bled 9‐10 days postoperatively and none had severe disease. CONCLUSION: Our protocol to prevent PTB in patients with BDs produced similar bleed rates to control patients in this study. Further studies are required to assess postoperative length of antifibrinolytic treatment in BD patients. LEVEL OF EVIDENCE: III. |
format | Online Article Text |
id | pubmed-8356851 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83568512021-08-15 Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders Pai, Kavya Desai, Harsh Stein, Dagmar Cole, Stephanie Laryngoscope Investig Otolaryngol PEDIATRICS AND DEVELOPMENT OBJECTIVE: Tonsil/adenoidectomy (T/A) is a commonly performed procedure with an average post‐tonsillectomy bleed (PTB) rate between 3 and 5%. Patients with bleeding disorders (BDs) are believed to have an increased risk of PTB. We hypothesize that our medical management of BD patients using a combination of DDAVP/antifibrinolytic agents has a similar PTB rate to control patients. This study suggests a standardized protocol for patients with BDs to avoid PTB. METHODS: A retrospective cohort study was completed for patients with BD who underwent tonsillectomy or T/A at Promedica Toledo or Flower Hospital between 2013 and 2020. Exclusion criteria included incomplete records, diagnosis of BD after surgery, and inability to find age and sex matched control. We defined the control group as patients who underwent T/A without BD. The following variables were collected: age, sex, medical history, BD severity, medications, type of surgery, indication for surgery, estimated blood loss (EBL), pre/postoperative medications, PTB status, and post‐PTB intervention. RESULTS: A total of 164 patient charts were reviewed. There were 82 patients in both cohorts. The BDs represented were platelet function disorder (80.5%), von Willebrand disease (14.6%), and others such as Factor VII and IX deficiency (4.9%). Of the BD patients included, 13.4% had severe disease. There was no significant difference between the age, sex, EBL, and PTB rates. Of the 8 BD patients with PTB, 62% bled 9‐10 days postoperatively and none had severe disease. CONCLUSION: Our protocol to prevent PTB in patients with BDs produced similar bleed rates to control patients in this study. Further studies are required to assess postoperative length of antifibrinolytic treatment in BD patients. LEVEL OF EVIDENCE: III. John Wiley & Sons, Inc. 2021-06-10 /pmc/articles/PMC8356851/ /pubmed/34401515 http://dx.doi.org/10.1002/lio2.589 Text en © 2021 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC on behalf of The Triological Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | PEDIATRICS AND DEVELOPMENT Pai, Kavya Desai, Harsh Stein, Dagmar Cole, Stephanie Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders |
title | Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders |
title_full | Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders |
title_fullStr | Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders |
title_full_unstemmed | Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders |
title_short | Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders |
title_sort | postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders |
topic | PEDIATRICS AND DEVELOPMENT |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356851/ https://www.ncbi.nlm.nih.gov/pubmed/34401515 http://dx.doi.org/10.1002/lio2.589 |
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