Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma

OBJECTIVES: Patients with laryngeal squamous cell carcinoma (LSCC) often fail radiation therapy (RT), when received as monotherapy or in combination with other treatment modalities. Mechanisms for RT failure are poorly understood. We hypothesized that tumors failing RT would have increased rates of...

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Detalles Bibliográficos
Autores principales: Sheth, Siddharth, Farquhar, Douglas R., Schrank, Travis P., Stepp, Wesley, Mazul, Angela, Hayward, Michele, Lenze, Nicholas, Little, Paul, Jo, Heejoon, Major, M. Ben, Chera, Bhishamjit S., Zevallos, Jose P., Hayes, D. Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
HEAD AND NECK, AND TUMOR BIOLOGY
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356873/
https://www.ncbi.nlm.nih.gov/pubmed/34401494
http://dx.doi.org/10.1002/lio2.588

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