The expression of prosaposin and its receptors, GRP37 and GPR37L1, are increased in the developing dorsal root ganglion

Prosaposin (PSAP), a highly conserved glycoprotein, is a precursor of saposins A–D. Accumulating evidence suggests that PSAP is a neurotrophic factor, as well as a regulator of lysosomal enzymes. Recently, the orphan G-protein-coupled receptors GPR37 and GPR37L1 were recognized as PSAP receptors, bu...

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Detalles Bibliográficos
Autores principales: Taniguchi, Miho, Nabeka, Hiroaki, Yamamiya, Kimiko, Khan, Md. Sakirul Islam, Shimokawa, Tetsuya, Islam, Farzana, Doihara, Takuya, Wakisaka, Hiroyuki, Kobayashi, Naoto, Hamada, Fumihiko, Matsuda, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357083/
https://www.ncbi.nlm.nih.gov/pubmed/34379697
http://dx.doi.org/10.1371/journal.pone.0255958

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