The EcoCyc Database in 2021

The EcoCyc model-organism database collects and summarizes experimental data for Escherichia coli K-12. EcoCyc is regularly updated by the manual curation of individual database entries, such as genes, proteins, and metabolic pathways, and by the programmatic addition of results from select high-thr...

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Detalles Bibliográficos
Autores principales: Keseler, Ingrid M., Gama-Castro, Socorro, Mackie, Amanda, Billington, Richard, Bonavides-Martínez, César, Caspi, Ron, Kothari, Anamika, Krummenacker, Markus, Midford, Peter E., Muñiz-Rascado, Luis, Ong, Wai Kit, Paley, Suzanne, Santos-Zavaleta, Alberto, Subhraveti, Pallavi, Tierrafría, Víctor H., Wolfe, Alan J., Collado-Vides, Julio, Paulsen, Ian T., Karp, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357350/
https://www.ncbi.nlm.nih.gov/pubmed/34394059
http://dx.doi.org/10.3389/fmicb.2021.711077
Descripción
Sumario:The EcoCyc model-organism database collects and summarizes experimental data for Escherichia coli K-12. EcoCyc is regularly updated by the manual curation of individual database entries, such as genes, proteins, and metabolic pathways, and by the programmatic addition of results from select high-throughput analyses. Updates to the Pathway Tools software that supports EcoCyc and to the web interface that enables user access have continuously improved its usability and expanded its functionality. This article highlights recent improvements to the curated data in the areas of metabolism, transport, DNA repair, and regulation of gene expression. New and revised data analysis and visualization tools include an interactive metabolic network explorer, a circular genome viewer, and various improvements to the speed and usability of existing tools.

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