Cargando…

Oxypaeoniflorin Prevents Acute Lung Injury Induced by Lipopolysaccharide through the PTEN/AKT Pathway in a Sirt1-Dependent Manner

Acute lung injury (ALI) is featured by pulmonary edema, alveolar barrier injury, inflammatory response, and oxidative stress. The activation of Sirt1 could relieve lipopolysaccharide- (LPS-) induced murine ALI by maintaining pulmonary epithelial barrier function. Oxypaeoniflorin (Oxy) serves as a ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guohua, Fan, Tieyuan, Zhu, Rui, Wang, Juan, Xiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357472/ https://www.ncbi.nlm.nih.gov/pubmed/34394832 http://dx.doi.org/10.1155/2021/6878026

Ejemplares similares

Artesunate reduces sepsis-mediated acute lung injury in a SIRT1-dependent manner
por: Liu, Zhaohui, et al.
Publicado: (2023)

Electroacupuncture Pretreatment Exhibits Lung Protective and Anti-Inflammation Effects in Lipopolysaccharide-Induced Acute Lung Injury via SIRT1-Dependent Pathways
por: Luo, Dan, et al.
Publicado: (2022)

Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p‐Akt pathway in methamphetamine‐induced chronic lung injury
por: Wang, Xin, et al.
Publicado: (2020)

Genistein Ameliorates Ischemia/Reperfusion-Induced Renal Injury in a SIRT1-Dependent Manner
por: Li, Wei-Fang, et al.
Publicado: (2017)

Formononetin inhibits lipopolysaccharide-induced release of high mobility group box 1 by upregulating SIRT1 in a PPARδ-dependent manner
por: Hwang, Jung Seok, et al.
Publicado: (2018)

Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner
por: Zhuang, Jiawei, et al.
Publicado: (2022)

Adiponectin/AdiopR1 signaling prevents mitochondrial dysfunction and oxidative injury after traumatic brain injury in a SIRT3 dependent manner
por: Zhang, Shenghao, et al.
Publicado: (2022)

Loss of autophagy affects melanoma development in a manner dependent on PTEN status
por: Rosenfeldt, Mathias T., et al.
Publicado: (2021)

Dihydroartemisinin attenuates lipopolysaccharide-induced acute lung injury in mice by suppressing NF-κB signaling in an Nrf2-dependent manner
por: Huang, Xiao-Ting, et al.
Publicado: (2019)

Ex Vivo Neurogenesis within Enteric Ganglia Occurs in a PTEN Dependent Manner
por: Becker, Laren, et al.
Publicado: (2013)

[Retracted] SIRT1 promotes tumorigenesis of hepatocellular carcinoma through PI3K/PTEN/AKT signaling
por: Wang, Hanning, et al.
Publicado: (2023)

Myosin 1b Regulates Nuclear AKT Activation by Preventing Localization of PTEN in the Nucleus
por: Yu, Yi, et al.
Publicado: (2019)

Preventive Effects of Carnosine on Lipopolysaccharide-induced Lung Injury
por: Tanaka, Ken-Ichiro, et al.
Publicado: (2017)

Human monocytes respond to lipopolysaccharide (LPS) stimulation in a sex‐dependent manner
por: Campesi, Ilaria, et al.
Publicado: (2021)

SIRT1 Mediates FOXA2 Breakdown by Deacetylation in a Nutrient-Dependent Manner
por: van Gent, Rogier, et al.
Publicado: (2014)

The loss of cardiac SIRT3 decreases metabolic flexibility and proteostasis in an age-dependent manner
por: Li, Ping, et al.
Publicado: (2022)

Peptides GWN and GW protect kidney cells against Dasatinib induced mitochondrial injury in a SIRT1 dependent manner
por: Bhullar, Khushwant S., et al.
Publicado: (2021)

PTEN suppresses tumorigenesis by directly dephosphorylating Akt
por: Bu, Lang, et al.
Publicado: (2021)

Hypoxia promotes colorectal cancer cell migration and invasion in a SIRT1-dependent manner
por: Yu, Shentong, et al.
Publicado: (2019)

Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner
por: Quiñones, Mar, et al.
Publicado: (2021)

SIRT3 protects against early brain injury following subarachnoid hemorrhage via promoting mitochondrial fusion in an AMPK dependent manner
por: Wu, Xun, et al.
Publicado: (2020)

miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1
por: Liu, Miaomiao, et al.
Publicado: (2022)

Minnelide/Triptolide Impairs Mitochondrial Function by Regulating SIRT3 in P53-Dependent Manner in Non-Small Cell Lung Cancer
por: Kumar, Ajay, et al.
Publicado: (2016)

The Preventive Effects of Lactobacillus casei on Acute Lung Injury Induced by Lipopolysaccharide
por: Zhao, Lihui, et al.
Publicado: (2021)

Ginsenoside Rg3 Attenuates Lipopolysaccharide-Induced Acute Lung Injury via MerTK-Dependent Activation of the PI3K/AKT/mTOR Pathway
por: Yang, Jing, et al.
Publicado: (2018)

Mechanism of N-acetylcysteine in alleviating diabetic myocardial ischemia reperfusion injury by regulating PTEN/Akt pathway through promoting DJ-1
por: Li, Wenyuan, et al.
Publicado: (2020)

Overexpression of PTEN suppresses lipopolysaccharide-induced lung fibroblast proliferation, differentiation and collagen secretion through inhibition of the PI3-K-Akt-GSK3beta pathway
por: He, Zhengyu, et al.
Publicado: (2014)

Inhibition of IRS-1 by hepatitis C virus infection leads to insulin resistance in a PTEN-dependent manner
por: Gao, Ting-ting, et al.
Publicado: (2015)

Replicative Senescence in Human Fibroblasts Is Delayed by Hydrogen Sulfide in a NAMPT/SIRT1 Dependent Manner
por: Sanokawa-Akakura, Reiko, et al.
Publicado: (2016)

Hypoxic Training Ameliorates Skeletal Muscle Microcirculation Vascular Function in a Sirt3-Dependent Manner
por: Ma, Chunwei, et al.
Publicado: (2022)

Schisandrin Attenuates Lipopolysaccharide-Induced Lung Injury by Regulating TLR-4 and Akt/FoxO1 Signaling Pathways
por: Sun, Kai, et al.
Publicado: (2018)

Propofol reduces lipopolysaccharide‑induced cardiomyocyte injury in sepsis by activating SIRT1‑mediated autophagy
por: Du, Junwang, et al.
Publicado: (2023)

UVB induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratinocytes
por: Ming, Mei, et al.
Publicado: (2009)

AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration
por: Huang, Haoliang, et al.
Publicado: (2019)

Quercetin alleviates lipopolysaccharide-induced acute lung injury by inhibiting ferroptosis via the Sirt1/Nrf2/Gpx4 pathway
por: Deng, Shihua, et al.
Publicado: (2023)

Mangiferin Mitigates Lipopolysaccharide-Induced Lung Injury by Inhibiting NLRP3 Inflammasome Activation
por: Li, Ning, et al.
Publicado: (2021)

Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy
por: Zhao, Runmin, et al.
Publicado: (2021)

WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner
por: Brown, K, et al.
Publicado: (2017)

METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m(6)A-YTHDF2-dependent manner
por: Li, Jiaren, et al.
Publicado: (2022)

circPTEN suppresses colorectal cancer progression through regulating PTEN/AKT pathway
por: Li, Chen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0ekquq5kpg4q42bdrvhdunal0m