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Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions
BACKGROUND/AIMS: Cholecystitis can occur after the placement of covered self-expandable metallic stents for distal malignant biliary obstructions. We aimed to identify risk factors for cholecystitis following covered self-expandable metallic stent placement. METHODS: We investigated risk factors rel...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Society of Gastrointestinal Endoscopy
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357581/ https://www.ncbi.nlm.nih.gov/pubmed/33198440 http://dx.doi.org/10.5946/ce.2020.136 |
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author | Watanabe, Masafumi Okuwaki, Kosuke Woo, Jun Kida, Mitsuhiro Imaizumi, Hiroshi Iwai, Tomohisa Yamauchi, Hiroshi Kaneko, Toru Hasegawa, Rikiya Kurosu, Takahiro Minato, Naoki Haradome, Hiroki Koizumi, Wasaburo |
author_facet | Watanabe, Masafumi Okuwaki, Kosuke Woo, Jun Kida, Mitsuhiro Imaizumi, Hiroshi Iwai, Tomohisa Yamauchi, Hiroshi Kaneko, Toru Hasegawa, Rikiya Kurosu, Takahiro Minato, Naoki Haradome, Hiroki Koizumi, Wasaburo |
author_sort | Watanabe, Masafumi |
collection | PubMed |
description | BACKGROUND/AIMS: Cholecystitis can occur after the placement of covered self-expandable metallic stents for distal malignant biliary obstructions. We aimed to identify risk factors for cholecystitis following covered self-expandable metallic stent placement. METHODS: We investigated risk factors related to cholecystitis following covered self-expandable metallic stent placement in 118 patients with distal malignant biliary obstructions between January 1, 2015 and April 30, 2019. Endoscopic assessments and tumor invasion to the arteries feeding the gallbladder were determined by a pancreaticobiliary endoscopist and a radiologist, respectively. RESULTS: The median patient age was 72 years (men, 61.0%). The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct were observed in 35 (29.7%) and 35 (29.7%) patients, respectively. During the observation period (median, 179 days), cholecystitis occurred in 18 (15.3%) patients. Multivariate analysis revealed the flow of the contrast agent into the gallbladder (p=0.023) and tumor involvement in the orifice of the cystic duct (p=0.005) as significant independent risk factors associated with cholecystitis. CONCLUSIONS: The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct are potential independent risk factors for cholecystitis following the placement of covered self-expandable metallic stents. A follow-up prospective study is warranted to validate their influence. |
format | Online Article Text |
id | pubmed-8357581 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Society of Gastrointestinal Endoscopy |
record_format | MEDLINE/PubMed |
spelling | pubmed-83575812021-08-13 Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions Watanabe, Masafumi Okuwaki, Kosuke Woo, Jun Kida, Mitsuhiro Imaizumi, Hiroshi Iwai, Tomohisa Yamauchi, Hiroshi Kaneko, Toru Hasegawa, Rikiya Kurosu, Takahiro Minato, Naoki Haradome, Hiroki Koizumi, Wasaburo Clin Endosc Original Article BACKGROUND/AIMS: Cholecystitis can occur after the placement of covered self-expandable metallic stents for distal malignant biliary obstructions. We aimed to identify risk factors for cholecystitis following covered self-expandable metallic stent placement. METHODS: We investigated risk factors related to cholecystitis following covered self-expandable metallic stent placement in 118 patients with distal malignant biliary obstructions between January 1, 2015 and April 30, 2019. Endoscopic assessments and tumor invasion to the arteries feeding the gallbladder were determined by a pancreaticobiliary endoscopist and a radiologist, respectively. RESULTS: The median patient age was 72 years (men, 61.0%). The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct were observed in 35 (29.7%) and 35 (29.7%) patients, respectively. During the observation period (median, 179 days), cholecystitis occurred in 18 (15.3%) patients. Multivariate analysis revealed the flow of the contrast agent into the gallbladder (p=0.023) and tumor involvement in the orifice of the cystic duct (p=0.005) as significant independent risk factors associated with cholecystitis. CONCLUSIONS: The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct are potential independent risk factors for cholecystitis following the placement of covered self-expandable metallic stents. A follow-up prospective study is warranted to validate their influence. Korean Society of Gastrointestinal Endoscopy 2021-07 2020-11-17 /pmc/articles/PMC8357581/ /pubmed/33198440 http://dx.doi.org/10.5946/ce.2020.136 Text en Copyright © 2021 Korean Society of Gastrointestinal Endoscopy https://creativecommons.org/licenses/by-nc/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Watanabe, Masafumi Okuwaki, Kosuke Woo, Jun Kida, Mitsuhiro Imaizumi, Hiroshi Iwai, Tomohisa Yamauchi, Hiroshi Kaneko, Toru Hasegawa, Rikiya Kurosu, Takahiro Minato, Naoki Haradome, Hiroki Koizumi, Wasaburo Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
title | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
title_full | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
title_fullStr | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
title_full_unstemmed | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
title_short | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
title_sort | cholecystitis after placement of covered self-expandable metallic stents in patients with distal malignant biliary obstructions |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357581/ https://www.ncbi.nlm.nih.gov/pubmed/33198440 http://dx.doi.org/10.5946/ce.2020.136 |
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