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Outcomes of Endoscopic Ultrasound-Guided Biliary Drainage in Patients Undergoing Antithrombotic Therapy

BACKGROUND/AIMS: The Japan Gastroenterological Endoscopy Society (JGES) has published guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment. These guidelines classify endoscopic ultrasound-guided biliary drainage (EUS-BD) as a high-risk procedure. Nevertheless,...

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Autores principales: Okuno, Nozomi, Hara, Kazuo, Mizuno, Nobumasa, Haba, Shin, Kuwahara, Takamichi, Koda, Hiroki, Tajika, Masahiro, Tanaka, Tsutomu, Onishi, Sachiyo, Yamada, Keisaku, Miyano, Akira, Fumihara, Daiki, Elshair, Moaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Gastrointestinal Endoscopy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357599/
https://www.ncbi.nlm.nih.gov/pubmed/33596639
http://dx.doi.org/10.5946/ce.2020.194
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author Okuno, Nozomi
Hara, Kazuo
Mizuno, Nobumasa
Haba, Shin
Kuwahara, Takamichi
Koda, Hiroki
Tajika, Masahiro
Tanaka, Tsutomu
Onishi, Sachiyo
Yamada, Keisaku
Miyano, Akira
Fumihara, Daiki
Elshair, Moaz
author_facet Okuno, Nozomi
Hara, Kazuo
Mizuno, Nobumasa
Haba, Shin
Kuwahara, Takamichi
Koda, Hiroki
Tajika, Masahiro
Tanaka, Tsutomu
Onishi, Sachiyo
Yamada, Keisaku
Miyano, Akira
Fumihara, Daiki
Elshair, Moaz
author_sort Okuno, Nozomi
collection PubMed
description BACKGROUND/AIMS: The Japan Gastroenterological Endoscopy Society (JGES) has published guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment. These guidelines classify endoscopic ultrasound-guided biliary drainage (EUS-BD) as a high-risk procedure. Nevertheless, the bleeding risk of EUS-BD in patients undergoing antithrombotic therapy is uncertain. Therefore, this study aimed to assess the bleeding risk in patients undergoing antithrombotic therapy. METHODS: This single-center retrospective study included 220 consecutive patients who underwent EUS-BD between January 2013 and December 2018. We managed the withdrawal and continuation of antithrombotic agents according to the JGES guidelines. We compared the bleeding event rates among patients who received and those who did not receive antithrombotic agents. RESULTS: A total of 18 patients (8.1%) received antithrombotic agents and 202 patients (91.8%) did not. Three patients experienced bleeding events, with an overall bleeding event rate of 1.3% (3/220): one patient was in the antithrombotic group (5.5%) and two patients were in the non-antithrombotic group (0.9%) (p=0.10). All cases were moderate. The sole thromboembolic event (0.4%) was a cerebral infarction in a patient in the non-antithrombotic group. CONCLUSIONS: The rate of EUS-BD-related bleeding events was low. Even in patients receiving antithrombotic therapy, the bleeding event rates were not significantly different from those in patients not receiving antithrombotic therapy.
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spelling pubmed-83575992021-08-13 Outcomes of Endoscopic Ultrasound-Guided Biliary Drainage in Patients Undergoing Antithrombotic Therapy Okuno, Nozomi Hara, Kazuo Mizuno, Nobumasa Haba, Shin Kuwahara, Takamichi Koda, Hiroki Tajika, Masahiro Tanaka, Tsutomu Onishi, Sachiyo Yamada, Keisaku Miyano, Akira Fumihara, Daiki Elshair, Moaz Clin Endosc Original Article BACKGROUND/AIMS: The Japan Gastroenterological Endoscopy Society (JGES) has published guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment. These guidelines classify endoscopic ultrasound-guided biliary drainage (EUS-BD) as a high-risk procedure. Nevertheless, the bleeding risk of EUS-BD in patients undergoing antithrombotic therapy is uncertain. Therefore, this study aimed to assess the bleeding risk in patients undergoing antithrombotic therapy. METHODS: This single-center retrospective study included 220 consecutive patients who underwent EUS-BD between January 2013 and December 2018. We managed the withdrawal and continuation of antithrombotic agents according to the JGES guidelines. We compared the bleeding event rates among patients who received and those who did not receive antithrombotic agents. RESULTS: A total of 18 patients (8.1%) received antithrombotic agents and 202 patients (91.8%) did not. Three patients experienced bleeding events, with an overall bleeding event rate of 1.3% (3/220): one patient was in the antithrombotic group (5.5%) and two patients were in the non-antithrombotic group (0.9%) (p=0.10). All cases were moderate. The sole thromboembolic event (0.4%) was a cerebral infarction in a patient in the non-antithrombotic group. CONCLUSIONS: The rate of EUS-BD-related bleeding events was low. Even in patients receiving antithrombotic therapy, the bleeding event rates were not significantly different from those in patients not receiving antithrombotic therapy. Korean Society of Gastrointestinal Endoscopy 2021-07 2021-02-17 /pmc/articles/PMC8357599/ /pubmed/33596639 http://dx.doi.org/10.5946/ce.2020.194 Text en Copyright © 2021 Korean Society of Gastrointestinal Endoscopy https://creativecommons.org/licenses/by-nc/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Okuno, Nozomi
Hara, Kazuo
Mizuno, Nobumasa
Haba, Shin
Kuwahara, Takamichi
Koda, Hiroki
Tajika, Masahiro
Tanaka, Tsutomu
Onishi, Sachiyo
Yamada, Keisaku
Miyano, Akira
Fumihara, Daiki
Elshair, Moaz
Outcomes of Endoscopic Ultrasound-Guided Biliary Drainage in Patients Undergoing Antithrombotic Therapy
title Outcomes of Endoscopic Ultrasound-Guided Biliary Drainage in Patients Undergoing Antithrombotic Therapy
title_full Outcomes of Endoscopic Ultrasound-Guided Biliary Drainage in Patients Undergoing Antithrombotic Therapy
title_fullStr Outcomes of Endoscopic Ultrasound-Guided Biliary Drainage in Patients Undergoing Antithrombotic Therapy
title_full_unstemmed Outcomes of Endoscopic Ultrasound-Guided Biliary Drainage in Patients Undergoing Antithrombotic Therapy
title_short Outcomes of Endoscopic Ultrasound-Guided Biliary Drainage in Patients Undergoing Antithrombotic Therapy
title_sort outcomes of endoscopic ultrasound-guided biliary drainage in patients undergoing antithrombotic therapy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357599/
https://www.ncbi.nlm.nih.gov/pubmed/33596639
http://dx.doi.org/10.5946/ce.2020.194
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