Cargando…

Bead-Based Isolation of Circulating Tumor DNA from Pancreatic Cancer Patients Enables High Fidelity Next Generation Sequencing

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers and poses a challenge to the treating clinician. With the emergence of genomic profiling technologies, circulating tumor DNA (ctDNA) is increasingly recognized as a versatile biomarker for risk stratification...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balendran-Braun, Sukirthini, Kieler, Markus, Liebmann-Reindl, Sandra, Unseld, Matthias, Bianconi, Daniela, W Prager, Gerald, Streubel, Berthold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357621/ https://www.ncbi.nlm.nih.gov/pubmed/34393517 http://dx.doi.org/10.2147/CMAR.S308029

Ejemplares similares

Genetic diagnosis and clinical evaluation of severe fetal akinesia syndrome
por: Reischer, Theresa, et al.
Publicado: (2020)

Biochemical and genetic predictors of overall survival in patients with metastatic pancreatic cancer treated with capecitabine and nab-paclitaxel
por: Bianconi, Daniela, et al.
Publicado: (2017)

Genetic association in female stress urinary incontinence based on proteomic findings: a case-control study
por: Reischer, Theresa, et al.
Publicado: (2019)

Cross-over comparison and new chemotherapy regimens in metastatic pancreatic cancer
por: Kieler, Markus, et al.
Publicado: (2017)

A real-world analysis of second-line treatment options in pancreatic cancer: liposomal-irinotecan plus 5-fluorouracil and folinic acid
por: Kieler, Markus, et al.
Publicado: (2019)

Expression of CD98hc in Pancreatic Cancer and Its Role in Cancer Cell Behavior
por: Bianconi, Daniela, et al.
Publicado: (2022)

Plasma levels of interleukin-33 and soluble suppression of tumorigenicity 2 in patients with advanced pancreatic ductal adenocarcinoma undergoing systemic chemotherapy
por: Kieler, Markus, et al.
Publicado: (2018)

Impact of New Chemotherapy Regimens on the Treatment Landscape and Survival of Locally Advanced and Metastatic Pancreatic Cancer Patients
por: Kieler, Markus, et al.
Publicado: (2020)

Next-Generation Sequencing-based genomic profiling of brain metastases of primary ovarian cancer identifies high number of BRCA-mutations
por: Balendran, S., et al.
Publicado: (2017)

SERPINB7 Expression Predicts Poor Pancreatic Cancer Survival Upon Gemcitabine Treatment
por: Bianconi, Daniela, et al.
Publicado: (2018)

Integrins in the Spotlight of Cancer
por: Bianconi, Daniela, et al.
Publicado: (2016)

Enhanced expression of the stemness-related factors OCT4, SOX15 and TWIST1 in ectopic endometrium of endometriosis patients
por: Proestling, Katharina, et al.
Publicado: (2016)

Different Toxicity Profiles Predict Third Line Treatment Efficacy in Metastatic Colorectal Cancer Patients
por: Unseld, Matthias, et al.
Publicado: (2020)

Microvascular density assessed by CD31 predicts clinical benefit upon bevacizumab treatment in metastatic colorectal cancer: results of the PassionATE study, a translational prospective Phase II study of capecitabine and irinotecan plus bevacizumab followed by capecitabine and oxaliplatin plus bevacizumab or the reverse sequence in patients in mCRC
por: Bianconi, Daniela, et al.
Publicado: (2020)

Molecular pathology of cancer: how to communicate with disease
por: Birner, Peter, et al.
Publicado: (2016)

Feasibility of personalized treatment concepts in gastrointestinal malignancies: Sub-group results of prospective clinical phase II trial EXACT
por: Unseld, Matthias, et al.
Publicado: (2018)

Interim analysis of a real-world precision medicine platform for molecular profiling of metastatic or advanced cancers: MONDTI
por: Kieler, Markus, et al.
Publicado: (2019)

Results of the extended analysis for cancer treatment (EXACT) trial: a prospective translational study evaluating individualized treatment regimens in oncology
por: Prager, Gerald W., et al.
Publicado: (2019)

Case report: impressive response to pembrolizumab in a patient with mismatch-repair deficient metastasized colorectal cancer and bulky disease
por: Kieler, Markus, et al.
Publicado: (2016)

Haptic Fidelity: The Game Changer in Surgical Simulators for the Next Decade?
por: Favier, Valentin, et al.
Publicado: (2021)

CD98hc (SLC3A2) drives integrin-dependent renal cancer cell behavior
por: Poettler, Marina, et al.
Publicado: (2013)

Comparison of DC Bead-irinotecan and DC Bead-topotecan drug eluting beads for use in locoregional drug delivery to treat pancreatic cancer
por: Forster, Richard E. J., et al.
Publicado: (2010)

First evidence for the antitumor activity of nanoliposomal irinotecan with 5-fluorouracil and folinic acid in metastatic biliary tract cancer
por: Taghizadeh, Hossein, et al.
Publicado: (2020)

Interactions of EGFR/PTEN/mTOR-Pathway Activation and Estrogen Receptor Expression in Cervical Cancer
por: Bartl, Thomas, et al.
Publicado: (2023)

C-reactive protein and white blood cell count are adverse prognostic markers for patients with advanced cancer on parenteral nutrition in a palliative care unit setting: A retrospective cohort study
por: Kieler, Markus, et al.
Publicado: (2022)

The Sequencing Bead Array (SBA), a Next-Generation Digital Suspension Array
por: Akhras, Michael S., et al.
Publicado: (2013)

Next-Generation Autoantibody Testing by Combination of Screening and Confirmation—the CytoBead® Technology
por: Sowa, Mandy, et al.
Publicado: (2016)

CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells
por: Sokka, Joonas, et al.
Publicado: (2022)

“Nanofiltration” Enabled by Super-Absorbent Polymer Beads for Concentrating Microorganisms in Water Samples
por: Xie, Xing, et al.
Publicado: (2016)

Hydrogel-Encapsulated Beads Enable Proximity-Driven Encoded Library Synthesis and Screening
por: Cavett, Valerie, et al.
Publicado: (2023)

3D approaches to model the tumor microenvironment of pancreatic cancer
por: Tomás-Bort, Elena, et al.
Publicado: (2020)

Plasma Clot Properties in Patients with Pancreatic Cancer
por: Thaler, Johannes, et al.
Publicado: (2023)

High-fidelity deconvolution for acoustic-resolution photoacoustic microscopy enabled by convolutional neural networks
por: Feng, Fei, et al.
Publicado: (2022)

Rolling circle reverse transcription enables high fidelity nanopore sequencing of small RNA
por: Maguire, Sean, et al.
Publicado: (2022)

Bead-linked transposomes enable a normalization-free workflow for NGS library preparation
por: Bruinsma, Stephen, et al.
Publicado: (2018)

Targeted next-generation sequencing of circulating free DNA enables non-invasive tumor detection in myxoid liposarcomas
por: Eisenhardt, A. E., et al.
Publicado: (2022)

Chemically-Modified Sepharose 6B Beads for Collection of Circulating Tumor Cells
por: Chen, Haiyan, et al.
Publicado: (2023)

Fidelity
Publicado: (1864)

Fidelity
Publicado: (1879)

Fidelity
Publicado: (1873)

Cannot write session to /tmp/vufind_sessions/sess_mrcn2r8fb6o0k9g6nth2fjufjf