Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling

Medulloblastoma (MB) is a childhood malignant brain tumour comprising four main subgroups characterized by different genetic alterations and rate of mortality. Among MB subgroups, patients with enhanced levels of the c-MYC oncogene (MB(Group3)) have the poorest prognosis. Here we identify a previous...

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Detalles Bibliográficos
Autores principales: Nazio, Francesca, Po, Agnese, Abballe, Luana, Ballabio, Claudio, Diomedi Camassei, Francesca, Bordi, Matteo, Camera, Antonio, Caruso, Simona, Caruana, Ignazio, Pezzullo, Marco, Ferraina, Caterina, Milletti, Giacomo, Gianesello, Matteo, Reddel, Sofia, De Luca, Carmen Dolores, Ceglie, Donatella, Marinelli, Sara, Campello, Silvia, Papaleo, Elena, Miele, Evelina, Cacchione, Antonella, Carai, Andrea, Vinci, Maria, Velardi, Enrico, De Angelis, Biagio, Tiberi, Luca, Quintarelli, Concetta, Mastronuzzi, Angela, Ferretti, Elisabetta, Locatelli, Franco, Cecconi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357694/
https://www.ncbi.nlm.nih.gov/pubmed/34302498
http://dx.doi.org/10.1007/s00401-021-02347-7

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