Germline variants in hereditary breast cancer genes are associated with early age at diagnosis and family history in Guatemalan breast cancer

PURPOSE: Mutations in hereditary breast cancer genes play an important role in the risk for cancer. METHODS: Cancer susceptibility genes were sequenced in 664 unselected breast cancer cases from Guatemala. Variants were annotated with ClinVar and VarSome. RESULTS: A total of 73 out of 664 subjects (...

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Detalles Bibliográficos
Autores principales: Ren, Megan, Orozco, Anali, Shao, Kang, Albanez, Anaseidy, Ortiz, Jeremy, Cao, Boyang, Wang, Lusheng, Barreda, Lilian, Alvarez, Christian S., Garland, Lisa, Wu, Dongjing, Chung, Charles C., Wang, Jiahui, Frone, Megan, Ralon, Sergio, Argueta, Victor, Orozco, Roberto, Gharzouzi, Eduardo, Dean, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357728/
https://www.ncbi.nlm.nih.gov/pubmed/34196900
http://dx.doi.org/10.1007/s10549-021-06305-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357728/
https://www.ncbi.nlm.nih.gov/pubmed/34196900
http://dx.doi.org/10.1007/s10549-021-06305-5

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