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Decidualized endometrial stromal cells present with altered androgen response in PCOS

Hyperandrogenic women with PCOS show disrupted decidualization (DE) and placentation. Dihydrotestosterone (DHT) is reported to enhance DE in non-PCOS endometrial stromal cells (eSC(Ctrl)); however, this has not been assessed in PCOS cells (eSC(PCOS)). Therefore, we studied the transcriptome profile...

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Detalles Bibliográficos
Autores principales: Khatun, Masuma, Meltsov, Alvin, Lavogina, Darja, Loid, Marina, Kask, Keiu, Arffman, Riikka K., Rossi, Henna-Riikka, Lättekivi, Freddy, Jääger, Kersti, Krjutškov, Kaarel, Rinken, Ago, Salumets, Andres, Piltonen, Terhi T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357821/
https://www.ncbi.nlm.nih.gov/pubmed/34381107
http://dx.doi.org/10.1038/s41598-021-95705-0