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Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking
Complement is an enzymatic humoral pattern-recognition defence system of the body. Non-specific deposition of blood biomolecules on nanomedicines triggers complement activation through the alternative pathway, but complement-triggering mechanisms of nanomaterials with dimensions comparable to or sma...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357934/ https://www.ncbi.nlm.nih.gov/pubmed/34381048 http://dx.doi.org/10.1038/s41467-021-24960-6 |