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Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking

Complement is an enzymatic humoral pattern-recognition defence system of the body. Non-specific deposition of blood biomolecules on nanomedicines triggers complement activation through the alternative pathway, but complement-triggering mechanisms of nanomaterials with dimensions comparable to or sma...

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Detalles Bibliográficos
Autores principales:	Wu, Lin-Ping, Ficker, Mario, Christensen, Jørn B., Simberg, Dmitri, Trohopoulos, Panagiotis N., Moghimi, Seyed M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357934/ https://www.ncbi.nlm.nih.gov/pubmed/34381048 http://dx.doi.org/10.1038/s41467-021-24960-6

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