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Molecular and functional characterization of detrusor PDGFRα positive cells in spinal cord injury-induced detrusor overactivity

Volume accommodation occurs via a novel mechanism involving interstitial cells in detrusor muscles. The interstitial cells in the bladder are PDGFRα(+), and they restrain the excitability of smooth muscle at low levels and prevents the development of transient contractions (TCs). A common clinical m...

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Detalles Bibliográficos
Autores principales: Lee, Ken, Park, Sang O, Choi, Pil-Cho, Ryoo, Seung-Bum, Lee, Haeyeong, Peri, Lauren E., Zhou, Tong, Corrigan, Robert D., Yanez, Andrew C., Moon, Suk B., Perrino, Brian A., Sanders, Kenton M., Koh, Sang Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357952/
https://www.ncbi.nlm.nih.gov/pubmed/34381120
http://dx.doi.org/10.1038/s41598-021-95781-2